Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 18/20 | 0.61 |
| ▸ | PGR | P06401 | 16/20 | 0.61 |
| ▸ | AR | P10275 | 13/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21729781 | 0.87 | NR3C1 (0.68) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL19042656 | 0.87 | NR3C1 (0.68) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL9019810 | 0.84 | PGR (0.65) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL9019798 | 0.84 | NR3C1 (0.67) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL9019846 | 0.84 | NR3C1 (0.83) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL21729697 | 0.84 | NR3C1 (0.64) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL9019833 | 0.84 | PGR (0.64) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL21729674 | 0.82 | NR3C1 (0.69) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL9019799 | 0.82 | NR3C1 (0.63) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL8651981 | 0.82 | NR3C1 (0.50) | NR3C1PGRARCYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567472-B1 | D-HOMO-(16-EN)-11 BETA-ARYL-4-ESTRENES, PROCESS FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | SCHERING AG (DE) | 1998-10-07 | — | — | EP | claimed |