Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | CASP3 | P42574 | 3/20 | 0.56 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654704 | 1.00 | MDM4 (0.59) | MDM4TP53CASP3MDM2KMT2A | |
| SCHEMBL9186701 | 1.00 | MDM4 (0.59) | MDM4TP53CASP3MDM2KMT2A | |
| SCHEMBL8653785 | 1.00 | MDM4 (0.59) | MDM4TP53CASP3MDM2KMT2A | |
| SCHEMBL16744159 | 0.94 | CASP3 (0.54) | MDM4TP53CASP3MDM2 | |
| SCHEMBL8227090 | 0.93 | CASP3 (0.55) | MDM4TP53CASP3MDM2KMT2A | |
| SCHEMBL8234371 | 0.93 | CASP3 (0.55) | MDM4TP53CASP3MDM2KMT2A | |
| SCHEMBL16744152 | 0.93 | CASP3 (0.55) | MDM4TP53CASP3MDM2KMT2A | |
| SCHEMBL16744153 | 0.92 | CASP3 (0.53) | MDM4TP53CASP3MDM2 | |
| SCHEMBL2308310 | 0.92 | MDM4 (0.54) | MDM4TP53CASP3MDM2KMT2A | |
| SCHEMBL120671 | 0.92 | MDM4 (0.54) | MDM4TP53CASP3MDM2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673388-B1 | DOUBLE CHAIN PEPTIDE COMPOUNDS HAVING HEMOREGULATORY ACTIVITY | NYCOMED IMAGING AS (NO) | 1998-10-14 | — | — | EP | disclosed |
| US-5610141-A | CELL DIVISION STIMULANT | NYCOMED IMAGING AS (NO) | 1997-03-11 | — | — | US | disclosed |
| WO-1993024523-A1 | DOUBLE CHAIN PEPTIDE COMPOUNDS HAVING HEMOREGULATORY ACTIVITY | HAFSLUND NYCOMED AS (NO) | 1993-12-09 | — | — | WO | disclosed |