Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.53 |
| ▸ | MDM4 | O15151 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TNF | P01375 | 3/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16744160 | 0.94 | TLR2 (0.53) | CASP3MDM4TP53TLR2TNF | |
| SCHEMBL16744142 | 0.94 | TLR2 (0.53) | CASP3MDM4TP53TLR2TNF | |
| SCHEMBL16744154 | 0.93 | TLR2 (0.54) | CASP3MDM4TP53TLR2TNF | |
| SCHEMBL8654704 | 0.92 | MDM4 (0.59) | CASP3MDM4TP53MDM2 | |
| SCHEMBL8653790 | 0.92 | MDM4 (0.59) | CASP3MDM4TP53MDM2 | |
| SCHEMBL9186701 | 0.92 | MDM4 (0.59) | CASP3MDM4TP53MDM2 | |
| SCHEMBL8653785 | 0.92 | MDM4 (0.59) | CASP3MDM4TP53MDM2 | |
| SCHEMBL16744156 | 0.92 | TLR2 (0.56) | CASP3MDM4TP53TLR2TNF | |
| SCHEMBL16744155 | 0.92 | TLR2 (0.56) | CASP3MDM4TP53TLR2TNF | |
| SCHEMBL16744157 | 0.92 | TLR2 (0.56) | CASP3MDM4TP53TLR2TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150148524-A1 | AMINO ACID ANALOGUES AND METHODS FOR THEIR SYNTHESIS | UNIV MONASH (AU) | 2015-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150148524-A1 | AMINO ACID ANALOGUES AND METHODS FOR THEIR SYNTHESIS | DAO, BCAT2, BCAT1 | CASP3 2406/4885MDM4 1684/4885TP53 722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.