Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.38 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA7 | P43166 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ANPEP | P15144 | 2/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.35 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3204936 | 0.77 | CA12 (0.40) | CA14CA12CA7CA9HTT | |
| SCHEMBL27412101 | 0.73 | CA12 (0.40) | CA14CA12CA7CA9HTT | |
| SCHEMBL13585410 | 0.71 | PMP22 (0.44) | KMT2ABLMSLC7A5 | |
| SCHEMBL13585408 | 0.71 | PMP22 (0.44) | KMT2ABLMSLC7A5 | |
| SCHEMBL14930545 | 0.71 | ALDH1A1 (0.46) | ANPEPRNPEPDNPEPNPC1RAB9A | |
| SCHEMBL19930276 | 0.71 | ALDH1A1 (0.46) | ANPEPRNPEPDNPEPNPC1RAB9A | |
| SCHEMBL27000228 | 0.69 | NR1H4 (0.36) | CA14CA12CA7CA9HTT | |
| SCHEMBL1300241 | 0.69 | GRIA1 (0.39) | CA14CA12CA7CA9HTT | |
| SCHEMBL5787485 | 0.68 | TAS2R14 (0.40) | CA12CA9ADAMTS4HTTMMP1 | |
| SCHEMBL27183432 | 0.67 | GRIA1 (0.38) | CA14CA12CA7CA9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756498-A | Sulfonylalkanoylamino hydroxyethylamino sulfonyl urea derivatives useful as retroviral protease inhibitors | G.D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | claimed |
| US-5756498-A | Sulfonylalkanoylamino hydroxyethylamino sulfonyl urea derivatives useful as retroviral protease inhibitors | G.D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |