Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556715 | 0.89 | — | — | |
| SCHEMBL7608268 | 0.87 | — | — | |
| SCHEMBL8553321 | 0.85 | AGTR2 (0.63) | AGTR2 | |
| SCHEMBL6551422 | 0.83 | AGTR2 (0.57) | AGTR2 | |
| SCHEMBL7612160 | 0.79 | AGTR1 (0.64) | AGTR2 | |
| SCHEMBL8653801 | 0.77 | AGTR2 (0.54) | AGTR2 | |
| SCHEMBL8653884 | 0.76 | AGTR2 (0.47) | AGTR2 | |
| SCHEMBL8969830 | 0.76 | — | — | |
| SCHEMBL8655254 | 0.76 | AGTR2 (0.49) | AGTR2 | |
| SCHEMBL7612386 | 0.76 | AGTR2 (0.51) | AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855392-A2 | Five-membered heterocycles having biphenylsulphonyl substituents, processes for the preparation thereof, their use as medicaments or diagnostic agent and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-29 | — | — | EP | disclosed |