Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 3/20 | 0.38 |
| ▸ | TYMP | P19971 | 2/20 | 0.37 |
| ▸ | TK2 | O00142 | 1/20 | 0.37 |
| ▸ | TK1 | P04183 | 1/20 | 0.37 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657464 | 0.96 | TYMS (0.35) | TYMSTYMPTK2TK1RNASE1 | |
| SCHEMBL8654350 | 0.88 | TYMS (0.42) | TYMSTYMPTK2TK1 | |
| SCHEMBL8654520 | 0.86 | TYMS (0.37) | TYMSTYMPRNASE1 | |
| SCHEMBL8657468 | 0.84 | TYMS (0.39) | TYMSTYMPTK2TK1 | |
| SCHEMBL8650972 | 0.84 | TK2 (0.52) | TYMSTYMPTK2TK1 | |
| SCHEMBL8510099 | 0.84 | TK2 (0.52) | TYMSTYMPTK2TK1 | |
| SCHEMBL8654230 | 0.83 | TK1 (0.40) | TYMSTYMPTK2TK1RNASE1 | |
| SCHEMBL8654233 | 0.83 | TK1 (0.40) | TYMSTYMPTK2TK1RNASE1 | |
| SCHEMBL8655343 | 0.82 | TK2 (0.46) | TYMSTYMPTK2TK1 | |
| SCHEMBL8655346 | 0.82 | TK2 (0.46) | TYMSTYMPTK2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763208-A | Oligonucleotides and their analogs capable of passive cell membrane permeation | GILEAD SCIENCES, INC. (US) | 1998-06-09 | — | — | US | disclosed |
| US-5633360-A | CONTAINS AT LEAST TWO NUCLEOSIDE RESIDUES AND INTERNUCLEOTIDE LINKAGES | GILEAD SCIENCES, INC. (US) | 1997-05-27 | — | — | US | disclosed |