Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654499 | 1.00 | CYP1A2 (0.52) | CYP1A2CYP2C9HPGDCYP3A4CYP2D6 | |
| SCHEMBL15281245 | 0.85 | APEX1 (0.55) | CYP1A2CYP2C9HPGDCYP3A4CYP2D6 | |
| SCHEMBL10769149 | 0.83 | ENPP2 (0.63) | CYP1A2CYP2C9HPGDCYP3A4CYP2D6 | |
| SCHEMBL3410648 | 0.82 | APEX1 (0.77) | CYP1A2CYP2C9HPGDCYP3A4CYP2D6 | |
| SCHEMBL11758267 | 0.82 | APEX1 (0.77) | CYP1A2CYP2C9HPGDCYP3A4CYP2D6 | |
| SCHEMBL12810338 | 0.81 | APEX1 (0.61) | CYP1A2CYP2C9HPGDCYP3A4CYP2D6 | |
| SCHEMBL11221594 | 0.81 | PRMT1 (0.56) | CYP1A2CYP2C9TSHRCYP2C19HSD17B10 | |
| SCHEMBL8648978 | 0.78 | CYP1A2 (0.52) | CYP1A2CYP2C9HPGDCYP3A4CYP2D6 | |
| SCHEMBL8648973 | 0.78 | CYP1A2 (0.52) | CYP1A2CYP2C9HPGDCYP3A4CYP2D6 | |
| SCHEMBL15268145 | 0.78 | ENPP2 (0.47) | CYP1A2CYP2C9HPGDCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5790627-A | Method and apparatus for observing a specimen using an X-ray microscope | RESEARCH DEVELOPMENT CORP. (JP) | 1998-08-04 | — | — | US | disclosed |