Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 2/20 | 0.56 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.56 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.56 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.56 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.56 |
| ▸ | GJB2 | P29033 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.47 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 4/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | TACR2 | P21452 | 1/20 | 0.45 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847408 | 1.00 | SSTR5 (0.56) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL9847357 | 1.00 | SSTR5 (0.56) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL6667042 | 0.92 | SSTR1 (0.58) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL22858228 | 0.92 | SSTR1 (0.58) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL22659920 | 0.92 | SSTR1 (0.58) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL18671703 | 0.92 | SSTR1 (0.58) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL10609599 | 0.92 | SSTR1 (0.58) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL26256369 | 0.92 | SSTR1 (0.58) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL13005380 | 0.92 | SSTR5 (0.58) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL8992036 | 0.92 | SSTR5 (0.58) | SSTR5SSTR1SSTR2SSTR4SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739333-B1 | SELECTIVE ASYMMETRIC HYDROGENATION OF DEHYDROAMINO ACID DERIVATIVES USING RHODIUM AND IRIDIUM DIPHOSPHINITE CARBOHYDRATE CATALYST COMPOSITIONS | DU PONT (US) | 1998-10-14 | — | — | EP | disclosed |
| US-5510507-A | COORDINATION CATALYSTS; EFFICIENT ENANTIOSELECTIVITY | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-04-23 | — | — | US | disclosed |
| US-5481006-A | PREPARATION OF INTERMEDIATES FOR PHARMACEUTICALS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-01-02 | — | — | US | disclosed |