SCHEMBL8655148

SCHEMBL8655148

CC=C(O)C(=O)Oc1cc[c]cc1

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.35
RAB9A P51151 1/20 0.33
LMNA P02545 3/20 0.32
HSD17B10 Q99714 2/20 0.32
GAA P10253 2/20 0.31
MAPT P10636 3/20 0.31
ALDH1A1 P00352 2/20 0.31
HSP90AA1 P07900 1/20 0.31
KMT2A Q03164 4/20 0.31
MEN1 O00255 2/20 0.31
HTT P42858 1/20 0.31
KDM4E B2RXH2 1/20 0.30
TTR P02766 1/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29141110 0.81 ELANE (0.46) ELANEHSD17B10GAAMAPTALDH1A1
SCHEMBL28009538 0.76 LMNA (0.38) ELANERAB9ALMNAHSD17B10GAA
SCHEMBL1171834 0.76 CA2 (0.38) RAB9ALMNAMAPTKMT2AMEN1
SCHEMBL243481 0.76 ELANE (0.54) ELANERAB9ALMNAHSD17B10GAA
Acetic Acid SCHEMBL28854456 0.75 LMNA (0.54) ELANELMNAHSD17B10GAAMAPT
SCHEMBL4977435 0.74 HTT (0.43) RAB9AGAAMAPTALDH1A1HTT
SCHEMBL128884 0.74 LMNA (0.58) ELANELMNAHSD17B10GAAMAPT
SCHEMBL487660 0.73 MAPT (0.45) ELANERAB9ALMNAHSD17B10GAA
SCHEMBL4365242 0.72 LMNA (0.31) LMNA
SCHEMBL7473598 0.72 LMNA (0.31) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5846640-A Polymer-fibre prepreg, a method for the preparation thereof as well as the use of said prepreg BIOXID OY (FI) 1998-12-08 US disclosed