Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 3/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658207 | 0.94 | LTA4H (0.46) | ACHEBCHELTA4HCHRM4FAAH | |
| SCHEMBL8658526 | 0.94 | LTA4H (0.46) | ACHEBCHELTA4HCHRM4FAAH | |
| SCHEMBL8655861 | 0.94 | LTA4H (0.46) | ACHEBCHELTA4HCHRM4FAAH | |
| SCHEMBL8655178 | 0.91 | ACHE (0.45) | ACHEBCHECHRM4FAAH | |
| SCHEMBL8661291 | 0.91 | KMT2A (0.45) | ACHEFAAH | |
| SCHEMBL8654508 | 0.91 | ACHE (0.44) | ACHEBCHECHRM4 | |
| SCHEMBL8657942 | 0.90 | LTA4H (0.47) | ACHEBCHELTA4HCHRM4FAAH | |
| SCHEMBL8657296 | 0.90 | LTA4H (0.47) | ACHEBCHELTA4HCHRM4FAAH | |
| SCHEMBL8657048 | 0.89 | ACHE (0.44) | ACHEBCHECHRM4 | |
| SCHEMBL8657796 | 0.89 | KMT2A (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |