Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4955640 | 0.83 | CYP2E1 (0.50) | HPGDSCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL1539107 | 0.83 | HPGDS (0.48) | HPGDSCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL2910946 | 0.82 | CYP2E1 (0.67) | HPGDSCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL7990801 | 0.77 | CYP2E1 (0.53) | HPGDSCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL9810711 | 0.77 | HPGDS (0.51) | HPGDSCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL13978068 | 0.77 | HPGDS (0.55) | HPGDSCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL29340888 | 0.76 | HPGDS (0.48) | HPGDSCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL1346083 | 0.75 | HPGDS (0.77) | HPGDSCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL651699 | 0.75 | CYP2E1 (0.50) | HPGDSCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL4865471 | 0.74 | PDE10A (0.49) | HPGDSCYP2E1CYP3A4CYP2A6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1067077-C | Erythromycin derivant and preparation method and usage of medicine thereof | ROUSSEL UCLAF (FR) | 2001-06-13 | — | — | CN | disclosed |
| CN-1059445-C | Novel derivatives of erythromycin, their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 2000-12-13 | — | — | CN | disclosed |
| EP-0716093-B1 | Erythromycin derivatives, their process of preparation and application as medicaments | HOECHST MARION ROUSSEL INC (FR) | 1998-10-21 | — | — | EP | disclosed |
| CN-1133291-A | Erythromycin derivant and preparation method and usage of medicine thereof | ROUSSEL UCLAF (FR) | 1996-10-16 | — | — | CN | disclosed |
| CN-1126997-A | Novel erythromycin derivatives, method for preparing same and use thereof as drugs | ROUSSEL UCLAF (FR) | 1996-07-17 | — | — | CN | disclosed |
| EP-0716093-A1 | Erythromycin derivatives, their process of preparation and application as medicaments | ROUSSEL UCLAF (FR) | 1996-06-12 | — | — | EP | disclosed |