Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SHMT1 | P34896 | 2/20 | 0.36 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8653784 | 0.90 | ANO1 (0.42) | ANO1P2RX7LMNAHPGDSMN1; SMN2 | |
| SCHEMBL8905510 | 0.90 | TRPV1 (0.44) | ANO1P2RX7TRPV1HDAC3HDAC1 | |
| SCHEMBL8654464 | 0.90 | SHMT1 (0.45) | P2RX7LMNAHPGDSMN1; SMN2SHMT1 | |
| SCHEMBL8657268 | 0.89 | P2RX7 (0.41) | ANO1P2RX7LMNAHPGDSMN1; SMN2 | |
| SCHEMBL8656926 | 0.89 | ANO1 (0.41) | ANO1P2RX7LMNAHPGDSMN1; SMN2 | |
| SCHEMBL8907303 | 0.89 | P2RX7 (0.39) | P2RX7LMNAHPGDALDH1A1GAA | |
| SCHEMBL8654200 | 0.89 | ANO1 (0.45) | ANO1P2RX7LMNAHPGDSMN1; SMN2 | |
| SCHEMBL8652029 | 0.88 | ANO1 (0.43) | ANO1P2RX7LMNAHPGDSMN1; SMN2 | |
| SCHEMBL8655537 | 0.88 | P2RX7 (0.40) | ANO1P2RX7LMNAHPGDSMN1; SMN2 | |
| SCHEMBL6482334 | 0.88 | GAA (0.44) | ANO1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847211-A | Substituted 1H-3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| US-5622917-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |