Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.45 |
| ▸ | BHMT | Q93088 | 3/20 | 0.34 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 3/20 | 0.33 |
| ▸ | NOS1 | P29475 | 3/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.32 |
| ▸ | TLR2 | O60603 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530109 | 0.86 | GSR (0.54) | GSRNOS3NOS1CPB2NOS2 | |
| SCHEMBL1345094 | 0.85 | GSR (0.47) | GSRCPB2RNPEPGNAI3GNAO1 | |
| Serine SCHEMBL3442575 | 0.85 | GSR (0.50) | GSRBHMTBHMT2NOS3NOS1 | |
| SCHEMBL6574895 | 0.84 | GSR (0.46) | GSRCPB2RNPEPGNAI3GNAO1 | |
| Lysine SCHEMBL6749781 | 0.83 | GSR (0.33) | GSR | |
| Alanine SCHEMBL4961214 | 0.81 | GSR (0.59) | GSRNOS3NOS1CPB2NOS2 | |
| Lysine SCHEMBL12469851 | 0.81 | GSR (0.65) | GSRBHMTBHMT2NOS3NOS1 | |
| SCHEMBL5586890 | 0.81 | GSR (0.40) | GSRRNPEPGNAI3GNAO1GNAI1 | |
| Lysine SCHEMBL8720001 | 0.80 | GSR (0.71) | GSRBHMTBHMT2NOS3NOS1 | |
| Lysine SCHEMBL938951 | 0.80 | GSR (0.71) | GSRBHMTBHMT2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057350-B1 | Recombinant DNA means and method | COLLABORATIVE RES INC (US) | 1998-10-21 | — | — | EP | disclosed |
| US-5525484-A | GENETICALLY ENGINEERED BACTERIA OR YEAST CELLS CONTAINING GENETIC MATERIAL FROM RECOMBINANT DNA WHICH CODES FOR BOVINE RENNIN | GENOME THERAPEUTICS CORP. (US) | 1996-06-11 | — | — | US | disclosed |
| US-5496711-A | GENETIC ENGINEERING WITH DNA USING FUNGI, YEASTS AND BACTERIA | GENOME THERAPEUTICS CORP. (US) | 1996-03-05 | — | — | US | disclosed |
| EP-0057350-A2 | Recombinant DNA means and method | Collaborative Research Inc. (US) | 1982-08-11 | — | — | EP | disclosed |