Serine

Serine

SCHEMBL3442575

CSCC[C@H](N)C(=O)OC(=O)[C@@H](N)CCCCN.N[C@@H](CO)C(=O)O

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.50
RNPEP Q9H4A4 2/20 0.35
NOS3 P29474 4/20 0.35
NOS1 P29475 4/20 0.35
NOS2 P35228 3/20 0.35
CPB2 Q96IY4 2/20 0.35
CYP2C19 P33261 1/20 0.35
THPO P40225 1/20 0.35
BHMT Q93088 2/20 0.34
BHMT2 Q9H2M3 1/20 0.34
ARG1 P05089 3/20 0.33
ARG2 P78540 3/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
GNAI3 P08754 1/20 0.33
GNAO1 P09471 1/20 0.33
GNAI1 P63096 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid SCHEMBL15323994 0.91 BHMT (0.40) GSRRNPEPNOS3NOS1NOS2
Lysine SCHEMBL9614340 0.91 GSR (0.44) GSRNOS3NOS1NOS2CYP2C19
Lysine SCHEMBL3442577 0.90 GSR (0.62) GSRRNPEPNOS3NOS1NOS2
SCHEMBL1345094 0.90 GSR (0.47) GSRRNPEPCPB2GNAI3GNAO1
SCHEMBL6574895 0.89 GSR (0.46) GSRRNPEPCPB2GNAI3GNAO1
Lysine SCHEMBL8655644 0.86 GSR (0.57) GSRNOS3NOS1NOS2CYP2C19
SCHEMBL5586890 0.85 GSR (0.40) GSRRNPEPGNAI3GNAO1GNAI1
SCHEMBL8655643 0.85 GSR (0.45) GSRRNPEPNOS3NOS1NOS2
Serine SCHEMBL8696833 0.85 BHMT (0.40) RNPEPNOS3NOS1NOS2BHMT
Serine SCHEMBL3883233 0.85 BHMT (0.40) RNPEPNOS3NOS1NOS2BHMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7811797-B2 α-isomaltosylglucosaccharide-forming enzyme, process and uses of the same KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2010-10-12 US disclosed
US-7718404-B2 α-isomaltosylglucosaccharide-forming enzyme, process and uses of the same KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2010-05-18 US disclosed
US-7592160-B2 Processes for producing isomaltose and isomaltitol and use thereof KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2009-09-22 US disclosed
US-20080032350-A1 Alpha-isomaltosylglucosaccharide-forming enzyme, process and uses of the same KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2008-02-07 US disclosed
US-20080003651-A1 alpha-isomaltosylglucosaccharide-forming enzyme, process and uses of the same KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2008-01-03 US disclosed
US-7241606-B2 α-Isomaltosylglucosaccharide synthase, process for producing the same and use thereof KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2007-07-10 US disclosed
US-7192746-B2 α-Isomaltosyltransferase, process for producing the same and use thereof KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2007-03-20 US disclosed
US-20060240531-A1 Processes for producing isomaltose and isomaltitol and use thereof KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2006-10-26 US disclosed
US-20050009017-A1 Alpha-isomaltosyltransferase, process for producing the same and use thereof KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2005-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050009017-A1 Alpha-isomaltosyltransferase, process for producing the same and use thereof UGGT1, B4GALT1, GALE GSR 914/4885RNPEP 540/4885NOS3 676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.