Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667437 | 0.78 | GABBR2 (0.52) | DPP4F2 | |
| SCHEMBL2126869 | 0.77 | TACR1 (0.50) | DPP4F2TRPA1HTR2ATAAR1 | |
| SCHEMBL2126865 | 0.77 | TACR1 (0.50) | DPP4F2TRPA1HTR2ATAAR1 | |
| SCHEMBL5043328 | 0.76 | KDM4E (0.56) | DPP4F2ADRA2AADRA2CLMNA | |
| SCHEMBL15916220 | 0.76 | KDM4E (0.56) | DPP4F2ADRA2AADRA2CLMNA | |
| SCHEMBL605463 | 0.76 | KDM4E (0.56) | DPP4F2ADRA2AADRA2CLMNA | |
| SCHEMBL2065907 | 0.76 | KDM4E (0.56) | DPP4F2ADRA2AADRA2CLMNA | |
| SCHEMBL147622 | 0.76 | KDM4E (0.56) | DPP4F2ADRA2AADRA2CLMNA | |
| SCHEMBL3363663 | 0.76 | KDM4E (0.56) | DPP4F2ADRA2AADRA2CLMNA | |
| SCHEMBL1162359 | 0.76 | KDM4E (0.56) | DPP4F2ADRA2AADRA2CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842148-A1 | BENZENESULPHONAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USES THEREOF | SYNTHELABO (FR) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997006136-A1 | BENZENESULPHONAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USES THEREOF | SYNTHELABO (FR) | 1997-02-20 | — | — | WO | disclosed |