SCHEMBL3363663

SCHEMBL3363663

N[C@@H](CO)C(O)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.56
ADRA2A P08913 1/20 0.56
ADRA2C P18825 1/20 0.56
LMNA P02545 1/20 0.56
HIF1A Q16665 1/20 0.56
ALDH1A1 P00352 2/20 0.54
SLC6A2 P23975 1/20 0.50
SLC6A4 P31645 1/20 0.50
SLC6A3 Q01959 1/20 0.50
AOC3 Q16853 4/20 0.48
DPP4 P27487 2/20 0.44
F2 P00734 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15916220 1.00 KDM4E (0.56) KDM4EADRA2AADRA2CLMNAHIF1A
SCHEMBL605463 1.00 KDM4E (0.56) KDM4EADRA2AADRA2CLMNAHIF1A
SCHEMBL1162359 1.00 KDM4E (0.56) KDM4EADRA2AADRA2CLMNAHIF1A
SCHEMBL145000 1.00 KDM4E (0.56) KDM4EADRA2AADRA2CLMNAHIF1A
SCHEMBL5043328 1.00 KDM4E (0.56) KDM4EADRA2AADRA2CLMNAHIF1A
SCHEMBL2065907 1.00 KDM4E (0.56) KDM4EADRA2AADRA2CLMNAHIF1A
SCHEMBL147622 1.00 KDM4E (0.56) KDM4EADRA2AADRA2CLMNAHIF1A
Bromide SCHEMBL9771320 0.98 KDM4E (0.54) KDM4EADRA2AADRA2CLMNAHIF1A
Hydrochloric Acid SCHEMBL9779186 0.98 ALDH1A1 (0.57) KDM4EADRA2AADRA2CLMNAHIF1A
Benzoic Acid SCHEMBL6048463 0.87 DAO (0.48) KDM4EADRA2AADRA2CLMNAHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7071324-B2 Systems and methods for sequencing by hybridization BROWN UNIVERSITY RESEARCH FOUNDATION (US) 2006-07-04 US claimed
US-20030064382-A1 Systems and methods for sequencing by hybridization NABSYS 2.0 LLC 2003-04-03 US claimed
WO-2025133248-A1 DIASTEREOMERIC AMINOALCOHOL AND AMINOETHER SALTS OF 2-[(4R,S)-8-FLUORO-2-[4-(3-METHOXYPHENYL)PIPERAZIN-1-YL]-3-[2-METHOXY-5-(TRIFLUOROMETHYL)PHENYL]-3,4-DIHYDROQUINAZOLIN-4-YL]ACETIC ACID AND THEIR USE FOR ENANTIOMERIC SEPARATION AIC246 AG & CO. KG (DE) 2025-06-26 WO disclosed
EP-2895603-A1 SERINOL PRODUCTION IN GLYCEROL CATABOLISM DEFICIENT ESCHERICHIA COLI STRAINS BASF SE (DE) 2015-07-22 EP disclosed
WO-2014040888-A1 SERINOL PRODUCTION IN GLYCEROL CATABOLISM DEFICIENT ESCHERICHIA COLI STRAINS BASF SE (DE) 2014-03-20 WO disclosed
US-8247540-B2 Caged nucleotides and oligonucleotides and their application DEITERS ALEXANDER (US) 2012-08-21 US disclosed
US-20100099159-A1 CAGED NUCLEOTIDES AND OLIGONUCLEOTIDES AND THEIR APPLICATION DEITERS ALEXANDER 2010-04-22 US disclosed
US-20080247948-A1 STEREOISOMERS OF FATTY ACID ANALOGS FOR DIAGNOSTIC IMAGING MOLECULAR INSIGHT PHARMACEUTICALS, INC. 2008-10-09 US disclosed
US-20080247948-A1 STEREOISOMERS OF FATTY ACID ANALOGS FOR DIAGNOSTIC IMAGING MOLECULAR INSIGHT PHARMACEUTICALS, INC. 2008-10-09 US disclosed
US-7314609-B2 Stereoisomers of fatty acid analogs for diagnostic imaging MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2008-01-01 US disclosed
US-7314609-B2 Stereoisomers of fatty acid analogs for diagnostic imaging MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2008-01-01 US disclosed
US-20070128110-A1 STEREOISOMERS OF FATTY ACID ANALOGS FOR DIAGNOSTIC IMAGING MOLECULAR INSIGHT PHARMACEUTICALS,INC. 2007-06-07 US disclosed
US-20070128110-A1 STEREOISOMERS OF FATTY ACID ANALOGS FOR DIAGNOSTIC IMAGING MOLECULAR INSIGHT PHARMACEUTICALS,INC. 2007-06-07 US disclosed
US-7071324-B2 Systems and methods for sequencing by hybridization BROWN UNIVERSITY RESEARCH FOUNDATION (US) 2006-07-04 US disclosed
WO-2004052876-A1 SUBSTITUTED 4-PHENYL-[1,3]-DIOXANES JANSSEN PHARMACEUTICA, N.V. (BE) 2004-06-24 WO disclosed
US-20030064382-A1 Systems and methods for sequencing by hybridization NABSYS 2.0 LLC 2003-04-03 US disclosed
US-5334712-A Estrane or androstane pyridinyl alkyl or alkylphenyl amine steroids for antidiabetes and obesity THE UPJOHN COMPANY (US) 1994-08-02 US disclosed
EP-0101570-A1 Method for the resolution of racemic 2-CP-difluoromethoxy phenyl)-3-methylbutyric acid AMERICAN CYANAMID COMPANY (US) 1984-02-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099159-A1 CAGED NUCLEOTIDES AND OLIGONUCLEOTIDES AND THEIR APPLICATION RNGTT, NT5C3B, ADAR KDM4E 4011/4885ADRA2A 2481/4885ADRA2C 3408/4885
US-20080247948-A1 STEREOISOMERS OF FATTY ACID ANALOGS FOR DIAGNOSTIC IMAGING FFAR3, FFAR1, FFAR4 KDM4E 4732/4885ADRA2A 1034/4885ADRA2C 1614/4885
US-20070128110-A1 STEREOISOMERS OF FATTY ACID ANALOGS FOR DIAGNOSTIC IMAGING FFAR3, FFAR1, FFAR4 KDM4E 4732/4885ADRA2A 1034/4885ADRA2C 1614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.