Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 7/20 | 0.48 |
| ▸ | TPSD1 | Q9BZJ3 | 7/20 | 0.48 |
| ▸ | TPSG1 | Q9NRR2 | 7/20 | 0.48 |
| ▸ | CPN1 | P15169 | 1/20 | 0.45 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5969150 | 0.82 | TPSAB1 (0.46) | TPSAB1TPSD1TPSG1CPN1CPB2 | |
| SCHEMBL12514070 | 0.82 | TPSAB1 (0.46) | TPSAB1TPSD1TPSG1CPN1CPB2 | |
| SCHEMBL8830336 | 0.79 | TPSAB1 (0.45) | TPSAB1TPSD1TPSG1CPN1CPB2 | |
| SCHEMBL6222860 | 0.79 | TPSAB1 (0.55) | TPSAB1TPSD1TPSG1CPN1CPB2 | |
| SCHEMBL8830339 | 0.79 | TPSAB1 (0.45) | TPSAB1TPSD1TPSG1CPN1CPB2 | |
| Hydrochloric Acid SCHEMBL11079847 | 0.78 | TPSAB1 (0.53) | TPSAB1TPSD1TPSG1CPN1CPB2 | |
| SCHEMBL9059540 | 0.77 | F2 (0.46) | TPSAB1TPSD1TPSG1CPN1CPB2 | |
| SCHEMBL3163506 | 0.77 | NCF1 (0.48) | TPSAB1TPSD1TPSG1CPN1CPB2 | |
| SCHEMBL9381035 | 0.77 | F2 (0.46) | TPSAB1TPSD1TPSG1CPN1CPB2 | |
| SCHEMBL8357898 | 0.77 | F2 (0.46) | TPSAB1TPSD1TPSG1CPN1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | claimed |
| US-5627197-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-05-06 | — | — | US | claimed |