SCHEMBL8655830

SCHEMBL8655830

ClC(Cl)=CCOc1cc(Cl)c(OCc2ccc(Oc3ccccc3)cc2)c(Cl)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 4/20 0.42
FFAR4 Q5NUL3 2/20 0.41
PPARG P37231 1/20 0.39
RHEB Q15382 1/20 0.39
LTA4H P09960 1/20 0.39
HRH3 Q9Y5N1 1/20 0.39
MCL1 Q07820 1/20 0.37
S1PR1 P21453 1/20 0.36
PRKX P51817 1/20 0.36
ACVR1 Q04771 1/20 0.36
S1PR5 Q9H228 1/20 0.36
THRA P10827 1/20 0.36
THRB P10828 1/20 0.36
HTT P42858 1/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8657017 0.91 LMNA (0.45) FFAR1FFAR4LTA4HS1PR1PRKX
SCHEMBL8408601 0.91 KDM4E (0.41) PPARGS1PR1PRKXACVR1S1PR5
SCHEMBL8656061 0.90 FFAR1 (0.46) FFAR1FFAR4PPARG
SCHEMBL8407763 0.89 GSTP1 (0.41) FFAR1PPARGKDM4E
SCHEMBL8661414 0.88 MEN1 (0.34) FFAR1FFAR4RHEBTHRBMEN1
SCHEMBL8659551 0.86 CYP4F2 (0.47) FFAR1S1PR1PRKXACVR1S1PR5
SCHEMBL8656279 0.86 FFAR1 (0.41) FFAR1FFAR4PPARGHTTNPC1
SCHEMBL8655825 0.86 MAOB (0.41) FFAR1PPARGTHRB
SCHEMBL8405583 0.85 MAPT (0.45) RHEBMEN1KMT2ANR4A2
SCHEMBL8408499 0.85 KCNQ3 (0.37) FFAR1PPARGS1PR1S1PR5HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0722430-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 1998-10-21 EP disclosed