SCHEMBL8655872

SCHEMBL8655872

C=CCOC(=O)Nc1ccc(O)c(C(=O)O)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.57
KDM4E B2RXH2 3/20 0.57
ALDH1A1 P00352 3/20 0.57
KDM4C Q9H3R0 3/20 0.53
HSD17B10 Q99714 3/20 0.50
POLB P06746 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
CYP2D6 P10635 1/20 0.50
ATM Q13315 1/20 0.50
AKR1C3 P42330 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
PKM P14618 1/20 0.47
TSHR P16473 1/20 0.47
AKR1C2 P52895 1/20 0.47
AKR1C1 Q04828 1/20 0.47
HPGD P15428 1/20 0.45
NOX4 Q9NPH5 2/20 0.44
RGS12 O14924 1/20 0.44
EGFR P00533 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8655003 0.89 KMT2A (0.54) MAPTKDM4EALDH1A1KDM4CHSD17B10
SCHEMBL24133057 0.82 MEN1 (0.46) KDM4EHSD17B10MEN1KMT2ACYP2D6
SCHEMBL24132594 0.82 MEN1 (0.52) MAPTKDM4EALDH1A1HSD17B10POLB
SCHEMBL597309 0.81 MAPT (0.61) MAPTKDM4EALDH1A1KDM4CHSD17B10
SCHEMBL25000324 0.81 XDH (0.47) MAPTKDM4EALDH1A1HSD17B10POLB
SCHEMBL13272479 0.79 MAPT (0.58) MAPTKDM4EALDH1A1KDM4CHSD17B10
SCHEMBL8603040 0.79 KDM4C (0.62) MAPTKDM4EALDH1A1KDM4CHSD17B10
SCHEMBL9148847 0.79 MAPT (0.58) MAPTKDM4EALDH1A1KDM4CHSD17B10
SCHEMBL16885017 0.78 CSNK2A2 (0.60) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL8602553 0.78 SMN1; SMN2 (0.59) MAPTKDM4EALDH1A1KDM4CHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0630758-B1 Heat-sensitive recording material MITSUBISHI PAPER MILLS LTD (JP) 1998-10-07 EP disclosed
US-5466655-A STORAGE STABILITY MITSUBISHI PAPER MILLS LIMITED (JP) 1995-11-14 US disclosed