Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603040 | 0.88 | KDM4C (0.62) | MAPTALDH1A1KDM4EKDM4CHSD17B10 | |
| SCHEMBL8602686 | 0.88 | RAB9A (0.70) | MAPTALDH1A1KDM4EHSD17B10CYP2D6 | |
| SCHEMBL1977674 | 0.88 | KMT2A (0.71) | MAPTALDH1A1KDM4EHSD17B10CYP2D6 | |
| SCHEMBL10765215 | 0.86 | KDM4C (0.60) | MAPTALDH1A1KDM4EKDM4CHSD17B10 | |
| SCHEMBL8604284 | 0.86 | RAB9A (0.59) | MAPTALDH1A1KDM4EKDM4CHSD17B10 | |
| SCHEMBL9149557 | 0.85 | KDM4E (0.52) | MAPTALDH1A1KDM4EKDM4CHSD17B10 | |
| SCHEMBL8655203 | 0.85 | KDM4E (0.54) | MAPTALDH1A1KDM4EKDM4CHSD17B10 | |
| SCHEMBL8602530 | 0.84 | KDM4C (0.64) | MAPTALDH1A1KDM4EKDM4CHSD17B10 | |
| SCHEMBL8602553 | 0.84 | SMN1; SMN2 (0.59) | MAPTALDH1A1KDM4EKDM4CHSD17B10 | |
| SCHEMBL8599913 | 0.84 | MAPT (0.68) | MAPTALDH1A1KDM4EKDM4CHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114858-B2 | Derivatives of 4- or 5-aminosalicylic acid | ANTIBE THERAPEUTICS INC. (CA) | 2012-02-14 | — | — | US | disclosed |
| US-8114857-B2 | Derivatives of 4- or 5-aminosalicylic acid | ANTIBE THERAPEUTICS INC. (CA) | 2012-02-14 | — | — | US | disclosed |
| EP-1883645-B1 | DERIVATIVES OF 4-OR 5-AMINOSALICYLIC ACID | ANTIBE THERAPEUTICS INC (CA) | 2011-06-29 | — | — | EP | disclosed |
| US-20110130368-A1 | DERIVATIVES OF 4- OR 5-AMINOSALICYLIC ACID | ANTIBE THERAPEUTICS INC. (CA) | 2011-06-02 | — | — | US | disclosed |
| US-20110098257-A1 | DERIVATIVES OF 4- OR 5-AMINOSALICYLIC ACID | ANTIBE THERAPEUTICS INC. (CA) | 2011-04-28 | — | — | US | disclosed |
| US-7910568-B2 | Inflammatory bowel disease, irritable bowel syndrome, Crohn's disease, ulcerative colitis, gastrointestinal disorders; prevention/treatment of colon cancer; releases hydrogen sulfide | ANTIBE THERAPEUTICS INC. (CA) | 2011-03-22 | — | — | US | disclosed |
| US-7879827-B2 | such as 5-amino-2-(2-Acetylamino-3-mercapto-propionyloxy)-benzoic acid, useful for the treatment of gastrointestinal disorders such as inflammatory bowel disease and irritable bowel syndrome, and for the prevention/treatment of colon cancer | ANTIBE THERAPEUTICS INC. (CA) | 2011-02-01 | — | — | US | disclosed |
| US-20090233886-A1 | DERIVATIVES OF 4- OR 5-AMINOSALICYLIC ACID | ANTIBE THERAPEUTICS INC. (CA) | 2009-09-17 | — | — | US | disclosed |
| US-7498355-B2 | Derivatives of 4- or 5-aminosalicylic acid | ANTIBE THERAPEUTICS INC. (CA) | 2009-03-03 | — | — | US | disclosed |
| US-20080207564-A1 | Derivaitves of 4-Or 5-Aminosalicylic Acid | ANTIBE THERAPEUTICS INC. (CA) | 2008-08-28 | — | — | US | disclosed |
| US-20070197479-A1 | Derivatives of 4- or 5-aminosalicylic acid | ANTIBE THERAPEUTICS INC. (CA) | 2007-08-23 | — | — | US | disclosed |
| WO-2006125293-A1 | DERIVATIVES OF 4- OR 5-AMINOSALICYLIC ACID | ANTIBE THERAPEUTICS INC. (CA) | 2006-11-30 | — | — | WO | disclosed |
| US-20060270635-A1 | Derivatives of 4- or 5-aminosalicylic acid | ANTIBE THERAPEUTICS INC. (CA) | 2006-11-30 | — | — | US | disclosed |
| WO-2006125295-A1 | DERIVATIVES OF 4-OR 5-AMINOSALICYLIC ACID | ANTIBE THERAPEUTICS INC. (CA) | 2006-11-30 | — | — | WO | disclosed |
| EP-0630758-B1 | Heat-sensitive recording material | MITSUBISHI PAPER MILLS LTD (JP) | 1998-10-07 | — | — | EP | disclosed |
| EP-0675002-B1 | Heat-sensitive recording material | FUJI PHOTO FILM CO LTD (JP) | 1998-02-25 | — | — | EP | disclosed |
| US-5476957-A | Dye for heat sensitive recording | MITSUI TOATSU CHEMICALS, INC. (JP) | 1995-12-19 | — | — | US | disclosed |
| US-5466655-A | STORAGE STABILITY | MITSUBISHI PAPER MILLS LIMITED (JP) | 1995-11-14 | — | — | US | disclosed |
| EP-0675002-A1 | Heat-sensitive recording material | FUJI PHOTO FILM CO., LTD. (JP) | 1995-10-04 | — | — | EP | disclosed |
| EP-0630758-A2 | Heat-sensitive recording material | MITSUBISHI PAPER MILLS, LTD. (JP) | 1994-12-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098257-A1 | DERIVATIVES OF 4- OR 5-AMINOSALICYLIC ACID | CBS, SI, APC | MAPT 3407/4885ALDH1A1 572/4885KDM4E 739/4885 |
| US-20080207564-A1 | Derivaitves of 4-Or 5-Aminosalicylic Acid | CBS, SI, TST | MAPT 2229/4885ALDH1A1 388/4885KDM4E 422/4885 |
| US-20090233886-A1 | DERIVATIVES OF 4- OR 5-AMINOSALICYLIC ACID | CBS, SI, APC | MAPT 3407/4885ALDH1A1 572/4885KDM4E 739/4885 |
| US-20110130368-A1 | DERIVATIVES OF 4- OR 5-AMINOSALICYLIC ACID | CBS, SI, APC | MAPT 3407/4885ALDH1A1 572/4885KDM4E 739/4885 |
| US-20060270635-A1 | Derivatives of 4- or 5-aminosalicylic acid | CBS, SI, APC | MAPT 3407/4885ALDH1A1 572/4885KDM4E 739/4885 |
| US-20070197479-A1 | Derivatives of 4- or 5-aminosalicylic acid | CBS, SI, APC | MAPT 3407/4885ALDH1A1 572/4885KDM4E 739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.