SCHEMBL8655964

SCHEMBL8655964

ClC(Cl)=CCOc1cc(Cl)c(OCc2cc(Oc3ccccc3)ccc2Br)c(Cl)c1

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RHEB Q15382 2/20 0.33
MAOB P27338 1/20 0.33
AOC3 Q16853 1/20 0.33
NAAA Q02083 2/20 0.32
HTT P42858 1/20 0.32
THRA P10827 6/20 0.32
THRB P10828 6/20 0.32
FFAR1 O14842 2/20 0.31
NR4A2 P43354 2/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
KMO O15229 1/20 0.31
FFAR4 Q5NUL3 1/20 0.31
LTA4H P09960 1/20 0.31
NR1H2 P55055 1/20 0.31
BAX Q07812 1/20 0.31
RORC P51449 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8409336 0.85 PARP10 (0.39) MAOBHTTTHRATHRBFFAR1
SCHEMBL8655830 0.84 FFAR1 (0.42) RHEBHTTTHRATHRBFFAR1
SCHEMBL8408641 0.84 LTA4H (0.40) RHEBMAOBNAAATHRATHRB
SCHEMBL8656061 0.82 FFAR1 (0.46) FFAR1FFAR4
SCHEMBL15382888 0.79 LTA4H (0.43) HTTFFAR1FFAR4LTA4H
SCHEMBL8409024 0.79 HTR2A (0.34) HTTFFAR4
SCHEMBL8405491 0.79 NR4A2 (0.43) MAOBHTTTHRBNR4A2NPC1
SCHEMBL8656279 0.78 FFAR1 (0.41) HTTFFAR1NPC1RAB9AFFAR4
SCHEMBL8408601 0.77 KDM4E (0.41) THRATHRBNPC1RAB9A
SCHEMBL8659509 0.76 MRGPRX4 (0.44) FFAR1KMOFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0722430-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 1998-10-21 EP disclosed
EP-0722430-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-07-24 EP disclosed
WO-1996004228-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-02-15 WO disclosed