Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11080897 | 0.79 | ALDH1A1 (0.51) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL4304223 | 0.78 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL2634981 | 0.77 | RAB9A (0.56) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL9599045 | 0.76 | NPC1 (0.63) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL7663329 | 0.75 | RAB9A (0.53) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL7742894 | 0.74 | GAA (0.47) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL966694 | 0.74 | MEN1 (0.69) | MEN1KMT2ASMN1; SMN2ALDH1A1GLA | |
| SCHEMBL2640927 | 0.74 | MEN1 (0.69) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11549494 | 0.73 | RAB9A (0.52) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL380050 | 0.73 | ALDH1A1 (0.76) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789588-A | BIOTIN DERIVATIIVES OF CARBODIIMIDE FOR NUCLEIC ACIDS AND PROTEINS | NISSHINBO INDUSTRIES, INC. (JP) | 1998-08-04 | — | — | US | disclosed |