Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 12/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.56 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8687308 | 0.89 | BCHE (0.69) | BCHEKDM4EL3MBTL1LMNAMITF | |
| SCHEMBL8688760 | 0.89 | BCHE (1.00) | BCHEKDM4EL3MBTL1LMNAMITF | |
| SCHEMBL3962959 | 0.85 | CHRM2 (0.63) | BCHEMAPTKMT2ASMN1; SMN2GRIN1 | |
| SCHEMBL8781195 | 0.84 | KDM4E (0.63) | BCHEKDM4EL3MBTL1GRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL7547505 | 0.79 | CHRM2 (0.85) | BCHEMAPTKMT2ASMN1; SMN2GRIN1 | |
| SCHEMBL3965713 | 0.79 | ALDH1A1 (0.60) | BCHEGRIN1GRIN2ACHRM2 | |
| SCHEMBL9264786 | 0.79 | BCHE (0.53) | BCHEKDM4EL3MBTL1KMT2A | |
| SCHEMBL9264780 | 0.79 | BCHE (0.53) | BCHEKDM4EL3MBTL1KMT2A | |
| SCHEMBL27489315 | 0.78 | BCHE (0.80) | BCHE | |
| SCHEMBL13888119 | 0.78 | BCHE (0.69) | BCHEKDM4EL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10310560-A | — | — | None | — | — | JP | disclosed |
| JP-H10310560-A | AMINE DERIVATIVE | MITSUBISHI CHEM CORP | 1998-11-24 | — | — | JP | disclosed |
| US-5807860-A | ACYLCOENZYME A:CHOLESTEROL ACYLTRANSFERASE INHIBITORS; HYPERLIPEMIA, ATHEROSCLEROSIS; ANTICHOLESTEROL AGENTS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0773218-A1 | N-(Piperazinylalkoxyphenyl)-N'phenylalkylurea derivatives as ACAT inhibitors for the treatment of atheroschlerosis | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-05-14 | — | — | EP | disclosed |