Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GALR2 | O43603 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19692378 | 0.87 | MAPT (0.41) | ALDH1A1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL6645249 | 0.86 | ALDH1A1 (0.49) | ALDH1A1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL1621780 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL30468543 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL8656095 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL29923851 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL25338637 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL20594744 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPTKMT2AL3MBTL1CRHBP | |
| SCHEMBL12985296 | 0.80 | MEN1 (0.44) | MAPTKMT2AMEN1POLBCYP1A2 | |
| SCHEMBL23830347 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MAPTKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811432-A | Azaoxindole derivatives | PFIZER INC (US) | 1998-09-22 | — | — | US | disclosed |
| EP-0436333-A2 | Azaoxindole derivatives | PFIZER INC. (US) | 1991-07-10 | — | — | EP | disclosed |