SCHEMBL8656100

SCHEMBL8656100

Sc1nnnn1-c1ccc(Cl)cc1Cl

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.60
NOTUM Q6P988 1/20 0.42
KMT2A Q03164 1/20 0.39
LMNA P02545 3/20 0.39
ALOX12 P18054 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30620395 1.00 L3MBTL1 (0.60) L3MBTL1NOTUMKMT2ALMNAALOX12
SCHEMBL6278254 0.86 L3MBTL1 (0.45) L3MBTL1NOTUMLMNA
SCHEMBL1249689 0.80 NOTUM (0.39) L3MBTL1NOTUMKMT2ALMNA
SCHEMBL28463382 0.79 L3MBTL1 (0.60) L3MBTL1NOTUMKMT2ALMNA
SCHEMBL3295145 0.79 KCNN4 (0.51) L3MBTL1NOTUM
SCHEMBL9610090 0.79 L3MBTL1 (0.40) L3MBTL1
SCHEMBL13297696 0.75 TSHR (0.38) L3MBTL1LMNA
SCHEMBL5685523 0.74 MAPT (0.56) L3MBTL1NOTUMLMNAALOX12NPSR1
SCHEMBL28449448 0.73 L3MBTL1 (0.57) L3MBTL1KMT2ALMNA
SCHEMBL1493397 0.72 P2RX7 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5124229-A Containing tertiary and secondary alkanolamines, mixture of 1-phenyl-1H-tetrazole-5-thiol and halogen derivative thereof AGFA-GEVAERT, N.V. (BE) 1992-06-23 US claimed
US-5063136-A Silver complex diffusion transfer reversal process using an mixture of an alkanolamine and two 1-(halogen-substituted phenyl)-1H-tetrazole-5-thiol derivatives; low carbon dioxide absorption AGFA-GEVAERT, N.V. (BE) 1991-11-05 US claimed
EP-0397927-A1 Processing liquid suitable for use in the silver complex diffusion transfer processing AGFA-GEVAERT N.V. (BE) 1990-11-22 EP claimed
EP-0397925-A1 Processing liquid for use in DTR-photography AGFA-GEVAERT N.V. (BE) 1990-11-22 EP claimed
JP-3243949-A None JP disclosed
EP-0436027-B1 METHOD OF TREATING SILVER HALIDE PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO LTD (JP) 1998-10-14 EP disclosed
US-5780198-A MULTILAYER; CONTAINS A HYDRAZINE NUCLEATING AGENT AND A REDOX COMPOUND CAPABLE OF RELEASING A DEVELOPMENT INHIBITOR WHEN THE REDOX COMPOUND IS OXIDIZED; ULTRAHIGH CONTRAST IMAGE WITH BROAD DOT GRADATION FUJI PHOTO FILM CO., LTD. (JP) 1998-07-14 US disclosed
EP-0442323-B1 Silver halide color reversal photographic material capable of providing interimage effect FUJI PHOTO FILM CO LTD (JP) 1997-10-15 EP disclosed
EP-0395069-B1 Silver halide photographic materials FUJI PHOTO FILM CO LTD (JP) 1996-07-10 EP disclosed
EP-0420005-B1 High contrast silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1996-07-10 EP disclosed
EP-0335319-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1996-06-05 EP disclosed
EP-0398285-B1 Silver halide photographic materials FUJI PHOTO FILM CO LTD (JP) 1995-09-13 EP disclosed
EP-0420005-A1 high contrast silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-04-03 EP disclosed
EP-0397927-A1 Processing liquid suitable for use in the silver complex diffusion transfer processing AGFA-GEVAERT N.V. (BE) 1990-11-22 EP disclosed
EP-0398285-A2 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1990-11-22 EP disclosed
EP-0397925-A1 Processing liquid for use in DTR-photography AGFA-GEVAERT N.V. (BE) 1990-11-22 EP disclosed
EP-0395069-A2 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1990-10-31 EP disclosed
EP-0393720-A2 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1990-10-24 EP disclosed
EP-0335319-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-10-04 EP disclosed
US-4737442-A INCLUDING A SENSITIZER AND A BLOCKED DEVELOPMENT RESTRAINER; FREE OF BLACK SPOTS FUJI PHOTO FILM CO., LTD. (JP) 1988-04-12 US disclosed