Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.53 |
| ▸ | ERN1 | O75460 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP2 | O95551 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464193 | 0.93 | CYP17A1 (0.61) | CYP17A1PTGS2PDGFRBPDGFRAPTGS1 | |
| SCHEMBL13906291 | 0.86 | CYP17A1 (0.55) | CYP17A1PTGS2PDGFRBPDGFRAPTGS1 | |
| SCHEMBL15605813 | 0.85 | CYP17A1 (0.58) | CYP17A1PTGS2PDGFRBPDGFRAPTGS1 | |
| SCHEMBL6368263 | 0.84 | PTGS2 (0.56) | CYP17A1PTGS2PDGFRBPDGFRAPTGS1 | |
| SCHEMBL8481713 | 0.83 | CYP17A1 (0.57) | CYP17A1PTGS2PDGFRBPDGFRAPTGS1 | |
| SCHEMBL19722074 | 0.83 | CYP17A1 (0.57) | CYP17A1PTGS2PDGFRBPDGFRAPTGS1 | |
| SCHEMBL10093049 | 0.83 | CYP17A1 (0.57) | CYP17A1PTGS2PDGFRBPDGFRAPTGS1 | |
| SCHEMBL7783072 | 0.83 | CYP17A1 (0.57) | CYP17A1PTGS2PDGFRBPDGFRAPTGS1 | |
| SCHEMBL17279129 | 0.82 | ERN1 (0.56) | CYP17A1PTGS2PDGFRBPDGFRAERN1 | |
| SCHEMBL14270106 | 0.81 | TUBB1 (0.49) | CYP17A1PTGS2PDGFRBPDGFRAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7399505-B2 | Fluorinated phenanthrenes and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2008-07-15 | — | — | US | disclosed |
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |