Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7494779 | 0.82 | HRH3 (0.50) | HRH3HTR4MAPTCYP3A4CYP2D6 | |
| SCHEMBL7403776 | 0.78 | ITGB3 (0.53) | ALDH1A1GAAITGB3ITGA2BHRH3 | |
| SCHEMBL8605949 | 0.75 | ITGB3 (0.44) | ALDH1A1GAAITGB3ITGA2BHRH3 | |
| SCHEMBL7329707 | 0.74 | MEN1 (0.54) | ALDH1A1GAAITGB3ITGA2BHRH3 | |
| Butane SCHEMBL27464815 | 0.72 | ITGB3 (0.47) | ALDH1A1GAAITGB3ITGA2BHRH3 | |
| SCHEMBL8605223 | 0.71 | ITGB3 (0.47) | ALDH1A1GAAITGB3ITGA2BHRH3 | |
| SCHEMBL7398606 | 0.71 | ITGB3 (0.44) | ALDH1A1GAAITGB3ITGA2BHRH3 | |
| SCHEMBL27464401 | 0.71 | ITGB3 (0.46) | ALDH1A1GAAITGB3ITGA2BHRH3 | |
| SCHEMBL8890453 | 0.70 | GAA (0.69) | ALDH1A1GAAL3MBTL1LMNAMAPT | |
| SCHEMBL8635833 | 0.69 | CYP2C9 (0.45) | ALDH1A1GAAITGB3ITGA2BHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825184-A1 | Heterocyclic derivatives as platelet aggregation inhibitors | ZENECA LIMITED (GB) | 1998-02-25 | — | — | EP | disclosed |