SCHEMBL8656278

SCHEMBL8656278

O=P(O)(O)OCCCCCCCCCCCCCCc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LPAR1 Q92633 8/20 0.55
S1PR4 O95977 3/20 0.51
S1PR1 P21453 3/20 0.51
S1PR3 Q99500 3/20 0.51
S1PR2 O95136 2/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
MAPT P10636 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
S1PR5 Q9H228 1/20 0.50
TSHR P16473 1/20 0.49
LPAR3 Q9UBY5 2/20 0.48
LPAR2 Q9HBW0 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29758247 1.00 LPAR1 (0.55) LPAR1S1PR4S1PR1S1PR3S1PR2
SCHEMBL26908453 1.00 LPAR1 (0.55) LPAR1S1PR4S1PR1S1PR3S1PR2
SCHEMBL26908447 1.00 LPAR1 (0.55) LPAR1S1PR4S1PR1S1PR3S1PR2
SCHEMBL10459319 1.00 LPAR1 (0.55) LPAR1S1PR4S1PR1S1PR3S1PR2
SCHEMBL2437208 1.00 LPAR1 (0.55) LPAR1S1PR4S1PR1S1PR3S1PR2
SCHEMBL26908448 1.00 LPAR1 (0.55) LPAR1S1PR4S1PR1S1PR3S1PR2
SCHEMBL4943606 1.00 LPAR1 (0.55) LPAR1S1PR4S1PR1S1PR3S1PR2
SCHEMBL10533195 1.00 LPAR1 (0.55) LPAR1S1PR4S1PR1S1PR3S1PR2
SCHEMBL7692985 1.00 LPAR1 (0.55) LPAR1S1PR4S1PR1S1PR3S1PR2
SCHEMBL5552741 0.98 L3MBTL1 (0.52) LPAR1S1PR4S1PR1S1PR3S1PR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0531585-B1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES LTD (GB) 1998-11-04 EP disclosed
US-5464549-A Oil soluble dispersants suitable for use in fuels and lubricants ETHYL CORPORATION (US) 1995-11-07 US disclosed
US-5358652-A Using 3,5-dihydrocarbyl-4-hydroxybenzylamine compound ETHYL PETROLEUM ADDITIVES, LIMITED (GB) 1994-10-25 US disclosed
US-5241003-A Post-treated polyisobutenyl succinimide; crankcase, transmission oils ETHYL PETROLEUM ADDITIVES, INC. (US) 1993-08-31 US disclosed
EP-0531585-A1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1993-03-17 EP disclosed
US-5137980-A Reacting polyisobutene with aacidic reactant; super atmospheric pressure; low tar rating ETHYL PETROLEUM ADDITIVES, INC. (US) 1992-08-11 US disclosed