SCHEMBL2437208

SCHEMBL2437208

O=P(O)(O)OCCCCCc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LPAR1 Q92633 8/20 0.55
S1PR4 O95977 3/20 0.51
S1PR1 P21453 3/20 0.51
S1PR3 Q99500 3/20 0.51
S1PR2 O95136 2/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
MAPT P10636 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
S1PR5 Q9H228 1/20 0.50
TSHR P16473 1/20 0.49
LPAR3 Q9UBY5 2/20 0.48
LPAR2 Q9HBW0 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8656278 1.00 LPAR1 (0.55) LPAR1S1PR4S1PR1S1PR3S1PR2
SCHEMBL29758247 1.00 LPAR1 (0.55) LPAR1S1PR4S1PR1S1PR3S1PR2
SCHEMBL26908453 1.00 LPAR1 (0.55) LPAR1S1PR4S1PR1S1PR3S1PR2
SCHEMBL26908447 1.00 LPAR1 (0.55) LPAR1S1PR4S1PR1S1PR3S1PR2
SCHEMBL10459319 1.00 LPAR1 (0.55) LPAR1S1PR4S1PR1S1PR3S1PR2
SCHEMBL26908448 1.00 LPAR1 (0.55) LPAR1S1PR4S1PR1S1PR3S1PR2
SCHEMBL4943606 1.00 LPAR1 (0.55) LPAR1S1PR4S1PR1S1PR3S1PR2
SCHEMBL10533195 1.00 LPAR1 (0.55) LPAR1S1PR4S1PR1S1PR3S1PR2
SCHEMBL7692985 1.00 LPAR1 (0.55) LPAR1S1PR4S1PR1S1PR3S1PR2
SCHEMBL5552741 0.98 L3MBTL1 (0.52) LPAR1S1PR4S1PR1S1PR3S1PR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240116075-A1 SUBSTRATE, SELECTIVE FILM DEPOSITION METHOD, DEPOSITION FILM OF ORGANIC MATTER, AND ORGANIC MATTER CENTRAL GLASS COMPANY, LIMITED (JP) 2024-04-11 US disclosed
EP-4287240-A1 SUBSTRATE, SELECTIVE FILM DEPOSITION METHOD, DEPOSITION FILM OF ORGANIC MATTER, AND ORGANIC MATTER Central Glass Company, Limited (JP) 2023-12-06 EP disclosed
CN-116685715-A Substrate, selective film deposition method, deposited film of organic substance, and organic substance 中央硝子株式会社 2023-09-01 CN disclosed
WO-2022163825-A1 SUBSTRATE, SELECTIVE FILM DEPOSITION METHOD, DEPOSITION FILM OF ORGANIC MATTER, AND ORGANIC MATTER セントラル硝子株式会社 2022-08-04 WO disclosed
US-8394356-B2 Diagnostic imaging contrast agents with extended blood retention LANTHEUS MEDICAL IMAGING, INC. (US) 2013-03-12 US disclosed
US-20120107249-A1 Diagnostic Imaging Contrast Agents with Extended Blood Retention LANTHEUS MEDICAL IMAGING, INC. (US) 2012-05-03 US disclosed
US-8017105-B2 Diagnostic imaging contrast agents with extended blood retention LANTHEUS MEDICAL IMAGING, INC. (US) 2011-09-13 US disclosed
US-7229606-B2 Diagnostic imaging contrast agents with extended blood retention EPIX PHARMACEUTICALS, INC. (US) 2007-06-12 US disclosed
US-20070020185-A1 Diagnostic imaging contrast agents with extended blood retention EPIX PHARMACEUTICALS, INC. A DELAWARE CORPORATION 2007-01-25 US disclosed
US-20070020184-A1 Diagnostic imaging contrast agents with extended blood retention EPIX PHARMACEUTICALS, INC. A DELAWARE CORPORATION 2007-01-25 US disclosed
EP-1043982-B1 LIPASE INHIBITING POLYMERS GENZYME CORP (US) 2005-11-09 EP disclosed
US-20040208827-A1 MEDICAL DIAGNOSIS; examining vasculature of a tissue, obtains a NMR image; reducing renal and hepatocellular uptake, lost less from the bloodstream, use a lower doses, retained by the blood for a prolonged period of time EPIX MEDICAL, INC., A DELAWARE CORPORATION 2004-10-21 US disclosed
US-20040202613-A1 Chelate compounds EPIX MEDICAL, INC., A DELAWARE CORPORATION 2004-10-14 US disclosed
US-6676929-B2 MEDICAL DIAGNOSIS; GADOFOSVESET EPIX MEDICAL, INC. 2004-01-13 US disclosed
US-20030180223-A1 Magnetic resonance imaging LANTHEUS MEDICAL IMAGING, INC. 2003-09-25 US disclosed
US-6572850-B1 Treating obesity by administering a polyether substituted with a pendant B-lactone group;reduction in fat hydrolysis and absorption GELTEX PHARMACEUTICALS, INC. 2003-06-03 US disclosed
US-6558657-B1 Synthetic polymer, carbohydrate or protein substituted with disulfide moiety that inhibits fat hydrolysis GELTEX PHARMACEUTICALS, INC. 2003-05-06 US disclosed
US-20020164289-A1 Medical diagnosis CITIZENS BANK, N.A. 2002-11-07 US disclosed
EP-0806968-A2 DIAGNOSTIC IMAGING CONTRAST AGENTS WITH EXTENDED BLOOD RETENTION Epix Medical, Inc. (US) 1997-11-19 EP disclosed
WO-1996023526-A2 DIAGNOSTIC IMAGING CONTRAST AGENTS WITH EXTENDED BLOOD RETENTION EPIX MEDICAL, INC. (US) 1996-08-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020164289-A1 Medical diagnosis FABP1, B2M, MB LPAR1 3325/4885S1PR4 521/4885S1PR1 898/4885
US-20030180223-A1 Magnetic resonance imaging BHMT, FABP1, FABP7 LPAR1 2941/4885S1PR4 292/4885S1PR1 483/4885
US-20040208827-A1 MEDICAL DIAGNOSIS; examining vasculature of a tissue, obtains a NMR image; reducing renal and hepatocellular uptake, lost less from the bloodstream, use a lower doses, retained by the blood for a prolonged period of time FABP1, BHMT, FABP3 LPAR1 3129/4885S1PR4 574/4885S1PR1 952/4885
US-20070020185-A1 Diagnostic imaging contrast agents with extended blood retention FABP1, B2M, BHMT LPAR1 2722/4885S1PR4 325/4885S1PR1 553/4885
US-20120107249-A1 Diagnostic Imaging Contrast Agents with Extended Blood Retention FABP1, B2M, BHMT LPAR1 2722/4885S1PR4 325/4885S1PR1 553/4885
US-20040202613-A1 Chelate compounds FABP1, BHMT, FABP3 LPAR1 3713/4885S1PR4 650/4885S1PR1 1043/4885
US-20070020184-A1 Diagnostic imaging contrast agents with extended blood retention FABP1, B2M, BHMT LPAR1 2722/4885S1PR4 325/4885S1PR1 553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.