Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ESRRA | P11474 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11030603 | 0.96 | MEN1 (0.43) | PPIANPC1KDM4EALDH1A1MAPK1 | |
| SCHEMBL11030721 | 0.93 | PYGL (0.41) | PPIANPC1KDM4EALDH1A1MEN1 | |
| SCHEMBL8661001 | 0.89 | ESRRA (0.48) | PPIANPC1KDM4EALDH1A1MAPK1 | |
| SCHEMBL8658967 | 0.87 | NPC1 (0.47) | PPIANPC1KDM4EALDH1A1MAPK1 | |
| SCHEMBL11031999 | 0.86 | GCGR (0.53) | NPC1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8659316 | 0.85 | ESRRA (0.50) | PPIANPC1KDM4EALDH1A1MAPK1 | |
| SCHEMBL8661548 | 0.84 | KDM4E (0.50) | PPIANPC1KDM4EALDH1A1MAPK1 | |
| SCHEMBL9132218 | 0.84 | KMT2A (0.44) | PPIANPC1KDM4EALDH1A1MAPK1 | |
| SCHEMBL10961870 | 0.83 | RAB9A (0.49) | NPC1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL10962502 | 0.83 | ESRRA (0.47) | PPIANPC1KDM4EALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5420163-A | Insecticides or miticides | CIBA-GEIGY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0211004-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | RHONE-POULENC NEDERLAND B.V. (NL) | 1987-02-25 | — | — | EP | disclosed |
| WO-1986003941-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1986-07-17 | — | — | WO | disclosed |
| US-4426385-A | Insecticidal bicyclooxyphenyl ureas | UNION CARBIDE CORPORATION (US) | 1984-01-17 | — | — | US | disclosed |
| EP-0050321-A2 | Novel bicyclooxyphenyl ureas, process for their preparation and pesticides containing them | UNION CARBIDE CORPORATION (US) | 1982-04-28 | — | — | EP | disclosed |