Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 13/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.42 |
| ▸ | MAPT | P10636 | 13/20 | 0.42 |
| ▸ | LMNA | P02545 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657600 | 0.89 | MEN1 (0.52) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL10606396 | 0.86 | MEN1 (0.47) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL9135345 | 0.83 | MAPT (0.47) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL11032023 | 0.82 | KMT2A (0.45) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL8676814 | 0.80 | MEN1 (0.43) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL8661480 | 0.79 | GCGR (0.40) | PTGDR2MEN1KMT2AMAPTLMNA | |
| SCHEMBL9132218 | 0.79 | KMT2A (0.44) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL9683664 | 0.78 | MEN1 (0.52) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL8659316 | 0.77 | ESRRA (0.50) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11244545 | 0.77 | MAPT (0.49) | MEN1KMT2AMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5420163-A | Insecticides or miticides | CIBA-GEIGY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0186297-B1 | PESTICIDAL BIPHENYLYLOXY AND BIPHENYLYLALKOXY ARYL ACYL UREA COMPOUNDS, A PROCESS FOR THEIR PREPARATION, PESTICIDAL COMPOSITIONS AND A METHOD OF CONTROLLING PESTS | RHONE-POULENC NEDERLAND B.V. (NL) | 1989-03-08 | — | — | EP | disclosed |
| EP-0211004-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | RHONE-POULENC NEDERLAND B.V. (NL) | 1987-02-25 | — | — | EP | disclosed |
| US-4638088-A | INSECTICIDES, MITICIDES | UNION CARBIDE CORPORATION (US) | 1987-01-20 | — | — | US | disclosed |
| WO-1986003941-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1986-07-17 | — | — | WO | disclosed |
| EP-0186297-A1 | Pesticidal biphenylyloxy and biphenylylalkoxy aryl acyl urea compounds, a process for their preparation, pesticidal compositions and a method of controlling pests | RHONE-POULENC NEDERLAND B.V. (NL) | 1986-07-02 | — | — | EP | disclosed |