Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | CTSG | P08311 | 1/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.50 |
| ▸ | CMA1 | P23946 | 1/20 | 0.50 |
| ▸ | TOP2A | P11388 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL645952 | 0.85 | HDAC3 (0.53) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL27439930 | 0.84 | PRSS1 (0.71) | L3MBTL1PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL27158903 | 0.80 | L3MBTL1 (0.67) | L3MBTL1SMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL7769202 | 0.79 | NPC1 (0.50) | L3MBTL1TOP2ACA12CA1CA2 | |
| SCHEMBL5009820 | 0.79 | MAPT (0.62) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL8423787 | 0.79 | HDAC3 (0.79) | HDAC3HDAC1HDAC2NCOR2HDAC8 | |
| SCHEMBL8658753 | 0.79 | CA12 (0.57) | HDAC3HDAC1HDAC2NCOR2HDAC8 | |
| Hydrochloric Acid SCHEMBL7773271 | 0.78 | NPC1 (0.49) | L3MBTL1TOP2ACA12CA1CA2 | |
| SCHEMBL2326874 | 0.78 | PRSS1 (0.60) | L3MBTL1PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL7898635 | 0.77 | L3MBTL1 (0.48) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869944-A1 | N-ACYLPIPERIDINYLCARBONYLAMINOCARBOXYLIC ACIDS AND THEIR USE AS GLYCOPROTEIN IIB/IIa ANTAGONISTS AND FIBRINOGEN-BLOOD PLATELETS BINDING INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |