SCHEMBL8657282

SCHEMBL8657282

O=P(O)(O)OCCCCCCCCCCCCCCCCCC1CCCC1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 7/20 0.50
LPAR2 Q9HBW0 6/20 0.50
LPAR1 Q92633 4/20 0.50
EPHX1 P07099 1/20 0.45
S1PR4 O95977 1/20 0.44
S1PR1 P21453 1/20 0.44
S1PR3 Q99500 1/20 0.44
S1PR5 Q9H228 1/20 0.44
SIGMAR1 Q99720 3/20 0.42
NAAA Q02083 1/20 0.40
METAP1 P53582 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10781105 0.98 LPAR3 (0.48) LPAR3LPAR2LPAR1EPHX1S1PR4
SCHEMBL10533858 0.98 LPAR3 (0.48) LPAR3LPAR2LPAR1EPHX1S1PR4
SCHEMBL8657353 0.98 LPAR3 (0.48) LPAR3LPAR2LPAR1EPHX1S1PR4
SCHEMBL10534523 0.98 LPAR3 (0.48) LPAR3LPAR2LPAR1EPHX1S1PR4
SCHEMBL27656930 0.98 LPAR3 (0.48) LPAR3LPAR2LPAR1EPHX1S1PR4
SCHEMBL17898555 0.98 LPAR3 (0.47) LPAR3LPAR2LPAR1EPHX1S1PR4
Ammonia Solution, Strong SCHEMBL27678528 0.96 LPAR3 (0.47) LPAR3LPAR2LPAR1EPHX1S1PR4
Phosphocholine SCHEMBL4657723 0.78 LPAR3 (0.47) LPAR3LPAR2LPAR1S1PR4S1PR1
SCHEMBL6258789 0.77 SIGMAR1 (0.43) LPAR3LPAR2EPHX1S1PR4S1PR1
SCHEMBL6257769 0.77 SIGMAR1 (0.43) LPAR3LPAR2EPHX1S1PR4S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0531585-B1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES LTD (GB) 1998-11-04 EP disclosed
US-5464549-A Oil soluble dispersants suitable for use in fuels and lubricants ETHYL CORPORATION (US) 1995-11-07 US disclosed
US-5358652-A Using 3,5-dihydrocarbyl-4-hydroxybenzylamine compound ETHYL PETROLEUM ADDITIVES, LIMITED (GB) 1994-10-25 US disclosed
US-5241003-A Post-treated polyisobutenyl succinimide; crankcase, transmission oils ETHYL PETROLEUM ADDITIVES, INC. (US) 1993-08-31 US disclosed
EP-0531585-A1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1993-03-17 EP disclosed
US-5137980-A Reacting polyisobutene with aacidic reactant; super atmospheric pressure; low tar rating ETHYL PETROLEUM ADDITIVES, INC. (US) 1992-08-11 US disclosed