Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.48 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10781105 | 1.00 | LPAR3 (0.48) | LPAR3LPAR2LPAR1EPHX1S1PR4 | |
| SCHEMBL10533858 | 1.00 | LPAR3 (0.48) | LPAR3LPAR2LPAR1EPHX1S1PR4 | |
| SCHEMBL27656930 | 1.00 | LPAR3 (0.48) | LPAR3LPAR2LPAR1EPHX1S1PR4 | |
| SCHEMBL10534523 | 1.00 | LPAR3 (0.48) | LPAR3LPAR2LPAR1EPHX1S1PR4 | |
| Ammonia Solution, Strong SCHEMBL27678528 | 0.98 | LPAR3 (0.47) | LPAR3LPAR2LPAR1EPHX1S1PR4 | |
| SCHEMBL8657282 | 0.98 | LPAR3 (0.50) | LPAR3LPAR2LPAR1EPHX1S1PR4 | |
| SCHEMBL17898555 | 0.96 | LPAR3 (0.47) | LPAR3LPAR2LPAR1EPHX1S1PR4 | |
| Phosphocholine SCHEMBL4657723 | 0.80 | LPAR3 (0.47) | LPAR3LPAR2LPAR1S1PR4S1PR1 | |
| SCHEMBL6257769 | 0.79 | SIGMAR1 (0.43) | LPAR3LPAR2EPHX1S1PR4S1PR1 | |
| SCHEMBL6258789 | 0.79 | SIGMAR1 (0.43) | LPAR3LPAR2EPHX1S1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531585-B1 | Oil additive concentrates and lubricants of enhanced performance capabilities | ETHYL PETROLEUM ADDITIVES LTD (GB) | 1998-11-04 | — | — | EP | disclosed |
| US-5587199-A | SUSPENDING IN AQUEOUS PHASE MAGNETITE IRON OXIDE PARTICLES, AMPHIPATHIC PHOSPHORIC ACID ESTER, NONIONIC SURFACTANT; SONICATING, MICROFLUIDIZING OR HEATING TO ORGANIZE AMPHIPATHIC COMPOUND INTO THREE-DIMENSIONAL STRUCTURE | BRACCO INTERNATIONAL B.V. (CH) | 1996-12-24 | — | — | US | disclosed |
| EP-0607401-B1 | PARTICLES FOR NMR IMAGING AND METHOD OF MANUFACTURE | BRACCO INT BV (NL) | 1996-10-30 | — | — | EP | disclosed |
| US-5545395-A | IRON OXIDE PARTICLES STABILIZED BY THREE-DIMENSIONAL SHELL LAYER CONTAINING MOLECULES OF AMPHIPATIC COMPOUND AND A NON-IONIC SURFACTANT; USED FOR MAGNETIC RESONANCE IMAGING; RESISTANT TO RAPID UPTAKE OF RETICULO-ENDOTHELIAL SYSTEM | BRACCO RESEARCH, S.A. (CH) | 1996-08-13 | — | — | US | disclosed |
| US-5464549-A | Oil soluble dispersants suitable for use in fuels and lubricants | ETHYL CORPORATION (US) | 1995-11-07 | — | — | US | disclosed |
| US-5464696-A | Iron oxide core with three-dimensional shell containing a phosphate compound in micelle form | BRACCO INTERNATIONAL B.V. (CH) | 1995-11-07 | — | — | US | disclosed |
| US-5358652-A | Using 3,5-dihydrocarbyl-4-hydroxybenzylamine compound | ETHYL PETROLEUM ADDITIVES, LIMITED (GB) | 1994-10-25 | — | — | US | disclosed |
| EP-0607401-A1 | PARTICLES FOR NMR IMAGING AND METHOD OF MANUFACTURE. | BRACCO INT BV (NL) | 1994-07-27 | — | — | EP | disclosed |
| WO-1994004197-A1 | PARTICLES FOR NMR IMAGING AND METHOD OF MANUFACTURE | SINTETICA S.A. (CH) | 1994-03-03 | — | — | WO | disclosed |
| US-5241003-A | Post-treated polyisobutenyl succinimide; crankcase, transmission oils | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1993-08-31 | — | — | US | disclosed |
| EP-0531585-A1 | Oil additive concentrates and lubricants of enhanced performance capabilities | ETHYL PETROLEUM ADDITIVES LIMITED (GB) | 1993-03-17 | — | — | EP | disclosed |
| US-5137980-A | Reacting polyisobutene with aacidic reactant; super atmospheric pressure; low tar rating | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1992-08-11 | — | — | US | disclosed |