Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2184301 | 0.80 | SLC16A3 (0.32) | ALDH1A1KMT2A | |
| SCHEMBL1554057 | 0.77 | HTR2A (0.48) | HTR2AHRH1KDM4EALDH1A1KMT2A | |
| SCHEMBL8655739 | 0.76 | HTR2A (0.31) | HTR2AHRH1TDP1 | |
| SCHEMBL13841149 | 0.76 | ALDH1A1 (0.48) | KDM4EALDH1A1MAPTKMT2ATDP1 | |
| Ammonia Solution, Strong SCHEMBL6699284 | 0.76 | HTR2A (0.46) | HTR2AHRH1KDM4EALDH1A1KMT2A | |
| SCHEMBL700217 | 0.75 | ADRA2A (0.44) | KDM4EALDH1A1MAPTKMT2ATDP1 | |
| SCHEMBL23516584 | 0.74 | KMT2A (0.39) | HTR2AHRH1KDM4EALDH1A1MAPT | |
| SCHEMBL15014119 | 0.74 | APP (0.41) | KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL21952689 | 0.74 | CHRM5 (0.50) | MAPTKMT2A | |
| SCHEMBL20893237 | 0.74 | MEN1 (0.43) | HTR2AKDM4EALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750552-A | ANTIULCER AGENTS | ARAX CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| US-5733922-A | Imidazole derivative, pharmaceutically acceptable salt thereof, and anti-ulcer drug including such derivative or salt | ARAX CO., LTD. (JP) | 1998-03-31 | — | — | US | disclosed |
| EP-0736527-A1 | Imadazoline derivative, possible tautomer thereof, process of manufacturing therefor, and vulnerary including such derivative or tautomer | ARAX CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |
| EP-0728747-A1 | Imidazole derivative, pharmaceutically acceptable salt thereof, process of manufacture therefor, and anti-ulcer drug including such derivative or salt | ARAX CO., LTD. (JP) | 1996-08-28 | — | — | EP | disclosed |