Thiophene

Thiophene

SCHEMBL8657478

c1cc2ccc1-2.c1ccsc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2E1 P05181 1/20 0.41
CYP2A6 P11509 1/20 0.41
CYP2B6 P20813 1/20 0.41
ALDH1A1 P00352 3/20 0.38
CYP3A4 P08684 3/20 0.33
TDP1 Q9NUW8 2/20 0.33
ESR1 P03372 2/20 0.33
MAPK1 P28482 1/20 0.33
TP53 P04637 1/20 0.33
ESR2 Q92731 1/20 0.33
CYP1A2 P05177 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MMP3 P08254 1/20 0.33
BCL2L1 Q07817 1/20 0.33
CYP2C9 P11712 1/20 0.30
HSD17B1 P14061 1/20 0.30
HSD17B2 P37059 1/20 0.30
SLC22A2 O15244 1/20 0.30
SLC22A1 O15245 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tannin Pyrogallol SCHEMBL28557820 0.90 ALDH1A1 (0.56) CYP2E1CYP2A6CYP2B6ALDH1A1CYP3A4
Biphenyl SCHEMBL8068963 0.86 ALDH1A1 (0.60) CYP2E1CYP2A6CYP2B6ALDH1A1CYP3A4
Biphenyl SCHEMBL16872437 0.86 ALDH1A1 (0.60) CYP2E1CYP2A6CYP2B6ALDH1A1CYP3A4
Biphenyl SCHEMBL15656401 0.86 ALDH1A1 (0.60) CYP2E1CYP2A6CYP2B6ALDH1A1CYP3A4
Benzidine SCHEMBL9812927 0.85 ALDH1A1 (0.61) ALDH1A1CYP3A4TDP1TP53CYP1A2
Thiophene SCHEMBL27514433 0.83 ALDH1A1 (0.56) CYP2E1CYP2A6CYP2B6ALDH1A1CYP3A4
Thiophene SCHEMBL27757987 0.79
Thiophene SCHEMBL7642100 0.79
Thiophene SCHEMBL225198 0.78
Thiophene SCHEMBL243 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0690074-B1 Photopolymerization initiator composition and photopolymerizable composition TOYO INK MFG CO (JP) 1998-09-02 EP disclosed