Biphenyl

Biphenyl

SCHEMBL16872437

c1ccc(-c2ccccc2)cc1.c1ccsc1.c1ccsc1.c1ccsc1.c1ccsc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.60
CYP2A6 P11509 2/20 0.57
CYP2B6 P20813 2/20 0.57
CYP2E1 P05181 1/20 0.57
SLC22A2 O15244 1/20 0.46
SLC22A1 O15245 1/20 0.46
SLC22A3 O75751 1/20 0.46
SLC6A4 P31645 1/20 0.46
MAPK1 P28482 2/20 0.43
TAAR1 Q96RJ0 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
NOTUM Q6P988 1/20 0.43
MMP3 P08254 1/20 0.43
BCL2L1 Q07817 1/20 0.43
ATM Q13315 1/20 0.39
PDPK1 O15530 1/20 0.39
NPC1 O15118 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL8068963 1.00 ALDH1A1 (0.60) ALDH1A1CYP2A6CYP2B6CYP2E1SLC22A2
Biphenyl SCHEMBL15656401 1.00 ALDH1A1 (0.60) ALDH1A1CYP2A6CYP2B6CYP2E1SLC22A2
Thiophene SCHEMBL27514433 0.97 ALDH1A1 (0.56) ALDH1A1CYP2A6CYP2B6CYP2E1SLC22A2
Tannin Pyrogallol SCHEMBL28557820 0.97 ALDH1A1 (0.56) ALDH1A1CYP2A6CYP2B6CYP2E1SLC22A2
SCHEMBL28887815 0.94 CYP2A6 (0.67) ALDH1A1CYP2A6CYP2B6CYP2E1SLC22A2
Thiophene SCHEMBL9437674 0.91 ALDH1A1 (0.50) ALDH1A1CYP2A6CYP2B6CYP2E1SLC22A2
Biphenyl SCHEMBL27397505 0.89 CYP2E1 (0.48) ALDH1A1CYP2A6CYP2B6CYP2E1SLC22A2
Thiophene SCHEMBL8657478 0.86 CYP2E1 (0.41) ALDH1A1CYP2A6CYP2B6CYP2E1SLC22A2
Thiophene SCHEMBL29118165 0.84 ALDH1A1 (0.71) ALDH1A1CYP2A6CYP2B6CYP2E1SLC22A2
Thiophene SCHEMBL27799989 0.84 MMP3 (0.71) CYP2A6CYP2B6CYP2E1TDP1MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2518075-B1 INDUCED LAYER MATERIAL FOR PREPARING NON-PLANAR METAL PHTHALOCYANINE WEAK EPITAXY GROWTH THIN FILM CHANGCHUN FLEXIBLE DISPLAY TECHNOLOGY CO LTD (CN) 2015-07-08 EP disclosed