Acrylic Acid

Acrylic Acid

SCHEMBL8657807

C=CC(=O)O.C=CC(=O)O.C=CC(=O)O.C=CC(=O)O.C=CC(=O)O.C=CC(=O)O.C=CC(=O)O.CCC(CO)(CO)CO.OCC(CO)(CO)CO.OCC(CO)(CO)COCC(CO)(CO)CO

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.47
ALDH1A1 P00352 2/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPK1 P28482 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HIF1A Q16665 1/20 0.43
LMNA P02545 1/20 0.36
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL5866609 0.98 THRB (0.49) THRBALDH1A1TP53CYP3A4MAPK1
Acrylic Acid SCHEMBL28078199 0.98 THRB (0.49) THRBALDH1A1TP53CYP3A4MAPK1
Acrylic Acid SCHEMBL28077934 0.98 THRB (0.49) THRBALDH1A1TP53CYP3A4MAPK1
Acrylic Acid SCHEMBL27584052 0.98 THRB (0.49) THRBALDH1A1TP53CYP3A4MAPK1
Acrylic Acid SCHEMBL29217848 0.98 THRB (0.49) THRBALDH1A1TP53CYP3A4MAPK1
Acrylic Acid SCHEMBL28145342 0.96 THRB (0.47) THRBALDH1A1TP53CYP3A4MAPK1
Methacrylic Acid SCHEMBL28072394 0.92 THRB (0.42) THRBALDH1A1TP53CYP3A4MAPK1
Methacrylic Acid SCHEMBL28080311 0.92 THRB (0.42) THRBALDH1A1TP53CYP3A4MAPK1
Methacrylic Acid SCHEMBL28075860 0.92 THRB (0.42) THRBALDH1A1TP53CYP3A4MAPK1
Acrylic Acid SCHEMBL21550097 0.91 ALDH1A1 (0.50) THRBALDH1A1TP53CYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0871907-A2 METHOD OF IMPARTING IMPACT RESISTANCE TO A PLASTIC OPHTHALMIC LENS, COMPOSITIONS FOR USE THEREIN AND A LENS PREPARED THEREBY ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 1998-10-21 EP disclosed
WO-1996023243-A1 METHOD OF IMPARTING IMPACT RESISTANCE TO A PLASTIC OPHTHALMIC LENS, COMPOSITIONS FOR USE THEREIN AND A LENS PREPARED THEREBY ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 1996-08-01 WO disclosed