Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 11/20 | 0.51 |
| ▸ | RARB | P10826 | 10/20 | 0.51 |
| ▸ | RARA | P10276 | 10/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.51 |
| ▸ | GOT1 | P17174 | 1/20 | 0.51 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8692906 | 0.89 | RARB (0.41) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL8659574 | 0.88 | RARB (0.63) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL8900640 | 0.88 | MEN1 (0.64) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL981497 | 0.82 | RARG (0.72) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL8656655 | 0.82 | RARG (0.48) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL8657215 | 0.81 | MEN1 (0.72) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL8458638 | 0.77 | RARG (0.55) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL8690840 | 0.76 | RARB (0.51) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL8660077 | 0.76 | RARA (0.38) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL7077371 | 0.75 | RARB (0.61) | RARGRARBRARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658553-B1 | Polycyclic aromatic compounds, pharmaceutical and cosmetic compositions containing them and uses thereof | CIRD GALDERMA (FR) | 1998-11-04 | — | — | EP | disclosed |
| EP-0658553-A1 | Polycyclic aromatic compounds, pharmaceutical compositions containing them and uses thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1995-06-21 | — | — | EP | disclosed |