Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8659695 | 0.83 | DDB1 (0.40) | MMP1RAB9AALDH1A1PKMCYP1A2 | |
| SCHEMBL12408240 | 0.76 | MMP1 (0.55) | MMP1LMNA | |
| SCHEMBL8663561 | 0.69 | HSD17B10 (0.51) | RAB9AALDH1A1PKMHPGDHSD17B10 | |
| SCHEMBL13621165 | 0.68 | ALDH1A1 (0.57) | GFERALDH1A1HSD17B10 | |
| SCHEMBL8667803 | 0.68 | ALDH1A1 (0.53) | ALDH1A1PKMHPGDCYP1A2CYP2C9 | |
| SCHEMBL9388351 | 0.65 | CYP3A4 (0.55) | PKMCYP1A2CYP3A4CYP2C9RECQL | |
| SCHEMBL1145473 | 0.65 | — | — | |
| SCHEMBL1145470 | 0.65 | — | — | |
| SCHEMBL7405579 | 0.65 | CYP1A2 (0.56) | ALDH1A1CYP1A2DAO | |
| SCHEMBL3419445 | 0.65 | CYP1A2 (0.56) | ALDH1A1CYP1A2CYP3A4CYP2C9HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767140-A | USEFUL FOR TREATING AIDS | SOUTHERN RESEARCH INSTITUTE (US) | 1998-06-16 | — | — | US | disclosed |