Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446367 | 0.93 | ITGB3 (0.48) | ITGB3ITGA2BABL1RIN1PKM | |
| SCHEMBL7442555 | 0.92 | ABL1 (0.40) | ITGB3ITGA2BABL1RIN1PKM | |
| SCHEMBL8658378 | 0.87 | KDM4E (0.41) | ITGB3ITGA2BABL1RIN1PKM | |
| SCHEMBL7459293 | 0.86 | ITGB3 (0.59) | ITGB3ITGA2B | |
| SCHEMBL7445388 | 0.85 | ITGB3 (0.45) | ITGB3ITGA2BABL1RIN1KMT2A | |
| SCHEMBL7444185 | 0.85 | KDM4E (0.47) | ITGB3ITGA2BABL1RIN1PKM | |
| SCHEMBL7442552 | 0.84 | KMT2A (0.40) | ABL1RIN1PKMKMT2AMAPT | |
| SCHEMBL7451021 | 0.82 | ITGB3 (0.49) | ITGB3ITGA2BKMT2AMAPTMEN1 | |
| SCHEMBL7447910 | 0.82 | ITGB3 (0.61) | ITGB3ITGA2B | |
| SCHEMBL7442559 | 0.81 | KMT2A (0.41) | ABL1RIN1PKMKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869944-A1 | N-ACYLPIPERIDINYLCARBONYLAMINOCARBOXYLIC ACIDS AND THEIR USE AS GLYCOPROTEIN IIB/IIa ANTAGONISTS AND FIBRINOGEN-BLOOD PLATELETS BINDING INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |