Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | F2R | P25116 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658382 | 0.93 | ITGB3 (0.44) | ITGB3ITGA2BKDM4EPKMSTS | |
| SCHEMBL7444185 | 0.92 | KDM4E (0.47) | ITGB3ITGA2BKDM4EPKMUSP30 | |
| SCHEMBL7445388 | 0.88 | ITGB3 (0.45) | ITGB3ITGA2BABL1RIN1KMT2A | |
| SCHEMBL7447910 | 0.87 | ITGB3 (0.61) | ITGB3ITGA2BF2R | |
| SCHEMBL7446356 | 0.86 | KDM4E (0.49) | ITGB3ITGA2BKDM4EPKMUSP30 | |
| SCHEMBL7450236 | 0.85 | ITGB3 (0.48) | ITGB3ITGA2BKDM4EPKMUSP30 | |
| SCHEMBL7818399 | 0.85 | ITGB3 (0.55) | ITGB3ITGA2BKDM4EPKMF2R | |
| SCHEMBL7447064 | 0.84 | ITGB3 (0.65) | ITGB3ITGA2BF2R | |
| SCHEMBL7451021 | 0.84 | ITGB3 (0.49) | ITGB3ITGA2BKMT2AF2RMEN1 | |
| SCHEMBL7444180 | 0.84 | KDM4E (0.47) | ITGB3ITGA2BKDM4EPKMUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384028-B1 | TREATMENT OF CARDIOVASCULAR DISORDERS, ANTICOAGULANTS AND VALVE REPLACEMENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| WO-1996029309-A1 | N-ACYLPIPERIDINYLCARBONYLAMINOCARBOXYLIC ACIDS AND THEIR USE AS GLYCOPROTEIN IIB/IIa ANTAGONISTS AND FIBRINOGEN-BLOOD PLATELETS BINDING INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-26 | — | — | WO | disclosed |