Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29676976 | 1.00 | KMT2A (0.50) | KMT2AKDM4EALOX15TSHRSIRT1 | |
| SCHEMBL8523119 | 0.84 | BCAT2 (0.46) | KMT2AKDM4EALOX15TSHRPKM | |
| SCHEMBL29918241 | 0.84 | BCAT2 (0.46) | KMT2AKDM4EALOX15TSHRPKM | |
| SCHEMBL11346171 | 0.83 | KMT2A (0.50) | KMT2AKDM4EALOX15TSHRSIRT1 | |
| SCHEMBL24629272 | 0.83 | KMT2A (0.46) | KMT2AKDM4EALOX15TSHRSIRT1 | |
| SCHEMBL13479783 | 0.81 | KMT2A (0.47) | KMT2AKDM4EALOX15TSHRSIRT1 | |
| SCHEMBL29035381 | 0.79 | MAOA (0.40) | KDM4EALDH1A1HSD17B10TDP1L3MBTL1 | |
| SCHEMBL148804 | 0.79 | KMT2A (0.57) | KMT2AKDM4EALOX15TSHRSIRT1 | |
| SCHEMBL29450202 | 0.79 | KMT2A (0.57) | KMT2AKDM4EALOX15TSHRSIRT1 | |
| Hydrochloric Acid SCHEMBL31097467 | 0.77 | KMT2A (0.55) | KMT2AKDM4EALOX15TSHRSIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3814351-A1 | COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2021-05-05 | — | — | EP | disclosed |
| EP-1666551-B1 | Ink for ink jet-recording curable through irradiation and method for preparing lithographic printing plates using the same | FUJIFILM CORP (JP) | 2010-02-17 | — | — | EP | disclosed |
| US-7635181-B2 | Ink for ink jet-recording curable through irradiation with a radioactive ray and method for preparing lithographic printing plates using the same | FUJIFILM CORPORATION (JP) | 2009-12-22 | — | — | US | disclosed |
| US-7635181-B2 | Ink for ink jet-recording curable through irradiation with a radioactive ray and method for preparing lithographic printing plates using the same | FUJIFILM CORPORATION (JP) | 2009-12-22 | — | — | US | disclosed |
| CN-1835934-A | oxazole derivatives as cyclooxygenase inhibitors | ASTELLAS PHARMA INC (JP) | 2006-09-20 | — | — | CN | disclosed |
| EP-0409617-B1 | Process for the preparation of metal complexes of thiolactams | ZENECA LTD (GB) | 1998-11-11 | — | — | EP | disclosed |
| US-5506253-A | REACTING ACETOXYPYRROLIDINONE COMPOUND WITH METAL TRIALKYLSILANOLATE | ZENECA LIMITED (GB) | 1996-04-09 | — | — | US | disclosed |
| US-5393750-A | Biocides | ZENECA, LIMITED (GB) | 1995-02-28 | — | — | US | disclosed |
| US-5120856-A | Bactericides, fungicides, algicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-06-09 | — | — | US | disclosed |
| EP-0409617-A2 | Thiolactams, process for their preparation and use as biocides | ZENECA LIMITED (GB) | 1991-01-23 | — | — | EP | disclosed |