1,4-Butanediol

1,4-Butanediol

SCHEMBL865857

C=CCOCC=C.OCCCCO

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA7 P43166 1/20 0.39
TSHR P16473 3/20 0.37
ALDH1A1 P00352 2/20 0.36
CA9 Q16790 1/20 0.36
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
POLB P06746 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.32
LMNA P02545 2/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL472068 0.97 CA1 (0.38) CA1CA2CA7TSHRALDH1A1
SCHEMBL6599869 0.97 CA1 (0.38) CA1CA2CA7TSHRALDH1A1
1,6-Hexanediol SCHEMBL472147 0.97 CA1 (0.38) CA1CA2CA7TSHRALDH1A1
1,5-Pentanediol SCHEMBL472091 0.97 CA1 (0.38) CA1CA2CA7TSHRALDH1A1
SCHEMBL472093 0.97 CA1 (0.38) CA1CA2CA7TSHRALDH1A1
SCHEMBL6600382 0.97 CA1 (0.38) CA1CA2CA7TSHRALDH1A1
1,3-Propanediol SCHEMBL1773540 0.94 CA1 (0.39) CA1CA2CA7TSHRALDH1A1
SCHEMBL9003130 0.90 MEN1 (0.39) CA1CA2CA7TSHRALDH1A1
Ethylene Glycol SCHEMBL29606 0.88 CA1 (0.42) CA1CA2CA7TSHRALDH1A1
SCHEMBL9003013 0.87 MEN1 (0.40) CA1CA2CA7TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4363409-A1 METHOD FOR PRODUCING ALKYLENE OXIDES Covestro Deutschland AG (DE) 2024-05-08 EP claimed
EP-4355482-A1 EPOXYDATION CATALYST SYSTEMS AND PROCESS FOR PREPARING EPOXIDES Covestro Deutschland AG (DE) 2024-04-24 EP claimed
US-20240002610-A1 SOLID-STATE METHOD FOR TREATING POLYAMIDE AND POLYESTER ARTICLES GREEN THEME TECHNOLOGIES, INC. 2024-01-04 US claimed
US-11760847-B2 Solid-state method for treating polyamide and polyester articles GREEN THEME TECHNOLOGIES, INC. (US) 2023-09-19 US claimed
WO-2023146769-A1 SOLID-STATE METHOD FOR TREATING SYNTHETIC THERMOPLASTIC ARTICLES Green Theme Technologies Inc. (US) 2023-08-03 WO claimed
US-20230235132-A1 SOLID-STATE METHOD FOR TREATING POLYAMIDE AND POLYESTER ARTICLES GREEN THEME TECHNOLOGIES, INC. 2023-07-27 US claimed
WO-2023274993-A1 METHOD FOR PRODUCING ALKYLENE OXIDES COVESTRO DEUTSCHLAND AG (DE) 2023-01-05 WO claimed
WO-2022263343-A1 EPOXYDATION CATALYST SYSTEMS AND PROCESS FOR PREPARING EPOXIDES COVESTRO DEUTSCHLAND AG (DE) 2022-12-22 WO claimed
US-20220177403-A1 REACTIVE SURFACTANTS STEPAN COMPANY 2022-06-09 US claimed
CN-1217904-C Dehydrogenation of alkylene glycol ethers to ether ketones and aldehydes ARCO CHEM TECH (US) 2005-09-07 CN claimed
CN-1474798-A Dehydrogenation of alkylene glycol ethers to ether detones and aldehydes ���ƻ�ѧ������˾ 2004-02-11 CN claimed
CN-112513118-B Curable compositions containing reactive functional compounds and polysiloxane resins, articles and coated articles made therefrom, and methods of reducing soil accumulation on substrates PPG工业俄亥俄公司 2024-06-28 CN disclosed
EP-4363409-A1 METHOD FOR PRODUCING ALKYLENE OXIDES Covestro Deutschland AG (DE) 2024-05-08 EP disclosed
EP-4355482-A1 EPOXYDATION CATALYST SYSTEMS AND PROCESS FOR PREPARING EPOXIDES Covestro Deutschland AG (DE) 2024-04-24 EP disclosed
CN-117820604-A Preparation method of alicyclic diglycidyl ether 江苏泰特尔新材料科技股份有限公司 2024-04-05 CN disclosed
EP-0957079-A1 NEW ETHER COMPOUNDS AND PROCESS FOR PRODUCING THE SAME Showa Denko Kabushiki Kaisha (JP) 1999-11-17 EP disclosed
US-5191123-A Catalytic decarboxylation with a metal oxide catalyst UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-03-02 US disclosed
EP-0478076-A2 Processes for the preparation of hydroxyl-containing compounds UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) 1992-04-01 EP disclosed
US-4864054-A Method for making cationically polymerizable aromatic polypropenyl ethers GENERAL ELECTRIC COMPANY (US) 1989-09-05 US disclosed
US-4309330-A EASILY CURABLE COATINGS HITACHI CHEMICAL COMPANY LTD. (JP) 1982-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220177403-A1 REACTIVE SURFACTANTS SMURF1, STS, ESD CA1 3891/4885CA2 4091/4885CA7 3869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.