Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.48 |
| ▸ | F10 | P00742 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8660044 | 0.90 | PTGS2 (0.43) | PTGS2PTGS1F10CA12CA2 | |
| SCHEMBL8659967 | 0.89 | PTGS2 (0.55) | PTGS2PTGS1F10CA12CA2 | |
| SCHEMBL8659097 | 0.87 | PTGS2 (0.44) | PTGS2PTGS1F10CA12CA2 | |
| SCHEMBL8660297 | 0.87 | ALDH1A1 (0.46) | PTGS2PTGS1F10CA12CA2 | |
| SCHEMBL8659720 | 0.87 | PTGS2 (0.58) | PTGS2PTGS1F10CA12CA2 | |
| SCHEMBL8658314 | 0.87 | PTGS2 (0.49) | PTGS2PTGS1F10CA12CA2 | |
| SCHEMBL8661512 | 0.86 | POLB (0.42) | PTGS2PTGS1F10CA12CA2 | |
| SCHEMBL8659195 | 0.84 | PTGS2 (0.49) | PTGS2PTGS1F10POLBMAPT | |
| SCHEMBL8661171 | 0.84 | PTGS2 (0.47) | PTGS2PTGS1F10CA12CA2 | |
| SCHEMBL8659269 | 0.84 | PTGS2 (0.50) | PTGS2PTGS1F10POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |