Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2333513 | 0.76 | KMT2A (0.53) | PTGS2PTGS1PDK2ALOX15TDP1 | |
| SCHEMBL30718118 | 0.76 | KMT2A (0.53) | PTGS2PTGS1PDK2ALOX15TDP1 | |
| SCHEMBL4068805 | 0.76 | ALOX15 (0.34) | ALOX15TDP1KMT2A | |
| SCHEMBL4073817 | 0.76 | DYRK1A (0.35) | ALOX15TDP1HTTHSD17B10KMT2A | |
| SCHEMBL2333074 | 0.76 | ALOX15 (0.31) | ALOX15TDP1 | |
| SCHEMBL2514710 | 0.76 | ALOX15 (0.31) | ALOX15TDP1 | |
| SCHEMBL29541279 | 0.73 | ALOX15 (0.32) | ALOX15TDP1KMT2A | |
| SCHEMBL7547799 | 0.72 | NPC1 (0.37) | PTGS2ALOX15TDP1LMNAKMT2A | |
| SCHEMBL9461473 | 0.72 | MAP4K4 (0.42) | ALOX15TDP1HTTMEN1LMNA | |
| SCHEMBL13993888 | 0.72 | PDK2 (0.40) | PDK2TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240190874-A1 | SMALL MOLECULE DEGRADERS OF ANDROGEN RECEPTOR | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2024-06-13 | — | — | US | disclosed |
| WO-2022187419-A1 | SMALL MOLECULE DEGRADERS OF ANDROGEN RECEPTOR | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2022-09-09 | — | — | WO | disclosed |
| US-5840904-A | Fluoro-pyridine-2,3-dicarboxylic anhydrides which are intermediates for herbicidal pyridine-2,3-dicarboximides | BASF AKTIENGESELLSCHAFT (DE) | 1998-11-24 | — | — | US | disclosed |
| US-5679622-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240190874-A1 | SMALL MOLECULE DEGRADERS OF ANDROGEN RECEPTOR | AR, CYP19A1, ESRRA | PTGS2 3290/4885PTGS1 2002/4885PDK2 2447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.