Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10676056 | 0.86 | CNR1 (0.33) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2333074 | 0.82 | ALOX15 (0.31) | ALOX15TDP1CYP11B1CYP11B2 | |
| SCHEMBL2514710 | 0.82 | ALOX15 (0.31) | ALOX15TDP1CYP11B1CYP11B2 | |
| SCHEMBL3345797 | 0.81 | GRM5 (0.33) | LMNACYP11B1CYP11B2 | |
| SCHEMBL14065330 | 0.78 | CALM1 (0.39) | NPC1ALDH1A1LMNAALOX15TDP1 | |
| SCHEMBL9215304 | 0.78 | GABRA1 (0.35) | ALDH1A1MAPTPARP1KMT2A | |
| SCHEMBL6598063 | 0.77 | NPC1 (0.41) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL30718118 | 0.76 | KMT2A (0.53) | PTGS2ALOX15TDP1KMT2A | |
| SCHEMBL2333513 | 0.76 | KMT2A (0.53) | PTGS2ALOX15TDP1KMT2A | |
| SCHEMBL4714309 | 0.74 | CYP11B1 (0.36) | LMNAMAPTMAPK1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112142713-A | Synthesis method of imazethapyr | 山东润博生物科技有限公司 | 2020-12-29 | — | — | CN | claimed |
| EP-0564083-A1 | Conversion of pyridine-2,3-dicarboxylic acid esters to their cyclic anhydrides | HOECHST CELANESE CORPORATION (US) | 1993-10-06 | — | — | EP | claimed |
| US-5208342-A | Hydrolysis and dehydration | HOECHST CELANESE CORPORATION (US) | 1993-05-04 | — | — | US | claimed |
| CN-112142713-A | Synthesis method of imazethapyr | 山东润博生物科技有限公司 | 2020-12-29 | — | — | CN | disclosed |
| CN-103524485-B | A kind of method of serialization synthesis imazethapyr | JIANGSU CHANGQING AGRICULTURAL CHEMISTRY CO., LTD. (CN) | 2015-09-09 | — | — | CN | disclosed |
| CN-103524485-A | Method for continuously synthesizing imazethapyr | JIANGSU CHANGQING AGROCHEMICAL CO LTD | 2014-01-22 | — | — | CN | disclosed |
| CN-102453022-B | Method for preparing imazethapyr | SINOCHEN CORP | 2013-09-11 | — | — | CN | disclosed |
| CN-102453022-B | Method for preparing imazethapyr | SINOCHEN CORP | 2013-09-11 | — | — | CN | disclosed |
| CN-102453022-A | Preparation method of imazethapyr | SINOCHEN CORP | 2012-05-16 | — | — | CN | disclosed |
| CN-102453022-A | Preparation method of imazethapyr | SINOCHEN CORP | 2012-05-16 | — | — | CN | disclosed |
| US-6441190-B1 | REACTING PYRIDINEDICARBOXYLIC ACID ANHYDRIDE OR PHTHALIC ANHYDRIDE COMPOUND WITH (R)2- AMINO-2,3-DIMETHYLBUTYRONITRILE IN PRESENCE OF WATER-FREE SOLVENT, HYDROLYSIS, TREATING WITH BASE; SEPARATION TO OBTAIN IMIDAZOLINONE COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 2002-08-27 | — | — | US | disclosed |
| US-20020077253-A1 | PROCESS FOR THE PREPARATION OF CHIRAL NICOTINIC, QUINOLINIC OR BENZOIC ACID IMIDAZOLINONE HERBICIDES | INTELLECTUAL PROPERTY DEPARTMENT (DE) | 2002-06-20 | — | — | US | disclosed |
| US-6339158-B1 | REACTING PYRIDINE OR QUINOLINE-2,3-DICARBOXYLIC ACID ANHYDRIDE DERIVATIVE WITH 2-AMINO-2,3-DIMETHYLBUTYRONITRILE IN PRESENCE OF NON-POLAR, WATER-FREE SOLVENT, TERTIARY AMINE, HYDROLYSIS, REACTING WITH BASE, SEPARATION, ACIDIFICATION | AMERICAN CYANAMID CO. | 2002-01-15 | — | — | US | disclosed |
| US-5322948-A | Reacting unsaturated diacid or derivative with hydroxylamine or a salt thereof to form N-hydroxy-2-aminobutane diacid derivative | HOECHST CELANESE CORPORATION (US) | 1994-06-21 | — | — | US | disclosed |
| EP-0511446-A2 | Process for preparing pyridinecarboxylic acid derivatives | HOECHST CELANESE CORPORATION (US) | 1992-11-04 | — | — | EP | disclosed |
| US-5098462-A | Herbicides | SANDOZ LTD. (CH) | 1992-03-24 | — | — | US | disclosed |
| US-5098466-A | Herbicides | SANDOZ LTD. (CH) | 1992-03-24 | — | — | US | disclosed |
| US-4748244-A | HERBICIDE INTERMEDIATES | CIBA-GEIGY CORPORATION (US) | 1988-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020077253-A1 | PROCESS FOR THE PREPARATION OF CHIRAL NICOTINIC, QUINOLINIC OR BENZOIC ACID IMIDAZOLINONE HERBICIDES | DDT, NQO2, NAPRT | NPC1 4814/4885ALDH1A1 1583/4885LMNA 2341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.