Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | IRS1 | P35568 | 1/20 | 0.31 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7657295 | 0.92 | CYP4F2 (0.34) | — | |
| SCHEMBL8659645 | 0.91 | CYP3A4 (0.33) | — | |
| SCHEMBL7660669 | 0.90 | FFAR1 (0.32) | — | |
| SCHEMBL8664824 | 0.87 | CYP3A4 (0.33) | — | |
| SCHEMBL8664160 | 0.86 | AKT1 (0.30) | AKT1IRS1GAB1 | |
| SCHEMBL7651219 | 0.85 | CYP4F2 (0.34) | — | |
| SCHEMBL8676360 | 0.85 | FDFT1 (0.36) | AKT1IRS1GAB1PPARGPPARA | |
| SCHEMBL8661860 | 0.85 | PPARG (0.32) | AKT1IRS1GAB1PPARGPPARA | |
| SCHEMBL8659725 | 0.83 | CYP3A4 (0.36) | AKT1IRS1GAB1 | |
| SCHEMBL6665048 | 0.83 | RARA (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750693-A | THIOCHROMANYL OR CHROMANYL COMPOUNDS AS ANTICARCINOGINIC AGENTS, SKIN DISORDERS AND ATHEROSCLEROSIS | ALLERGAN (US) | 1998-05-12 | — | — | US | disclosed |
| US-5677451-A | CONTROLLING CELL DIFFERENTIATION; SKIN DISORDERS; ANTICANCER AGENTS | ALLERGAN (US) | 1997-10-14 | — | — | US | disclosed |