SCHEMBL8660239

SCHEMBL8660239

CCCCCCCCCCCCCCCc1ccccc1C1OC1COCC1OC1c1ccccc1CCCCCCCCCCCCCCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 4/20 0.46
CYSLTR1 Q9Y271 4/20 0.46
LIPG Q9Y5X9 1/20 0.44
THRA P10827 1/20 0.38
THRB P10828 1/20 0.38
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
ALOX5 P09917 1/20 0.37
PTGS2 P35354 1/20 0.37
PPARA Q07869 3/20 0.36
BID P55957 3/20 0.35
MCL1 Q07820 3/20 0.35
BCL2L1 Q07817 2/20 0.35
BAK1 Q16611 2/20 0.35
KAT8 Q9H7Z6 2/20 0.35
PPARG P37231 2/20 0.35
EP300 Q09472 1/20 0.35
KAT2A Q92830 1/20 0.35
KAT2B Q92831 1/20 0.35
KAT5 Q92993 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9560315 0.85 CYSLTR2 (0.51) CYSLTR2CYSLTR1LIPGTHRATHRB
SCHEMBL9013116 0.80 CYSLTR2 (0.51) CYSLTR2CYSLTR1LIPGTHRATHRB
SCHEMBL7141369 0.80 CYSLTR2 (0.51) CYSLTR2CYSLTR1LIPGTHRATHRB
SCHEMBL9559966 0.76 CYP4F2 (0.53) CYSLTR2CYSLTR1LIPGTHRATHRB
SCHEMBL31606779 0.75 SPHK1 (0.46) LIPGTHRATHRBPTGS2
SCHEMBL4304168 0.74 CYSLTR2 (0.52) CYSLTR2CYSLTR1LIPGTHRATHRB
SCHEMBL27997497 0.72 CYSLTR2 (0.50) CYSLTR2CYSLTR1LIPGTHRATHRB
SCHEMBL2307568 0.72 CYSLTR2 (0.50) CYSLTR2CYSLTR1LIPGTHRATHRB
SCHEMBL27260116 0.72 CYSLTR2 (0.50) CYSLTR2CYSLTR1LIPGTHRATHRB
SCHEMBL379442 0.72 CYSLTR2 (0.50) CYSLTR2CYSLTR1LIPGTHRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4828771-A POLYEPOXIDES TOTO LTD. (JP) 1989-05-09 US claimed
EP-0872504-A1 CURABLE EPOXY RESIN COMPOSITION WHICH GIVES FLEXIBLE CURED ARTICLE ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1998-10-21 EP disclosed
US-4828771-A POLYEPOXIDES TOTO LTD. (JP) 1989-05-09 US disclosed
US-4797425-A EPOXY RESIN FROM BISPHENOL WITH AMIDE HARDENERS TOTO LTD. (JP) 1989-01-10 US disclosed
US-4542192-A Reactive hardenable polymer mixture and process for the preparation of hardened products therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1985-09-17 US disclosed