SCHEMBL27997497

SCHEMBL27997497

CCCCCCCCCCCCCCCCCCc1ccccc1C1CO1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 2/20 0.50
CYSLTR1 Q9Y271 2/20 0.50
LIPG Q9Y5X9 1/20 0.49
NR1H2 P55055 1/20 0.41
NR1H3 Q13133 1/20 0.41
TYR P14679 2/20 0.40
THRA P10827 2/20 0.40
THRB P10828 2/20 0.40
MEN1 O00255 1/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
ALOX5 P09917 1/20 0.40
MAPT P10636 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP2D6 P10635 1/20 0.40
DRD2 P14416 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL379442 1.00 CYSLTR2 (0.50) CYSLTR2CYSLTR1LIPGNR1H2NR1H3
SCHEMBL2307568 1.00 CYSLTR2 (0.50) CYSLTR2CYSLTR1LIPGNR1H2NR1H3
SCHEMBL27260116 1.00 CYSLTR2 (0.50) CYSLTR2CYSLTR1LIPGNR1H2NR1H3
SCHEMBL10931942 0.93 CYSLTR2 (0.42) CYSLTR2CYSLTR1LIPGTYRCYP3A4
Sulfuric Acid SCHEMBL8338601 0.90 CYSLTR2 (0.46) CYSLTR2CYSLTR1LIPGNR1H2NR1H3
SCHEMBL28606150 0.86 LIPG (0.41) CYSLTR2CYSLTR1LIPGTHRATHRB
SCHEMBL8020367 0.81 THRA (0.41) CYSLTR2CYSLTR1LIPGTHRATHRB
SCHEMBL27864215 0.80 CYSLTR2 (0.47) CYSLTR2CYSLTR1LIPGNR1H2NR1H3
SCHEMBL4304168 0.79 CYSLTR2 (0.52) CYSLTR2CYSLTR1LIPGNR1H2NR1H3
Bicarbonate SCHEMBL9187058 0.78 BID (0.48) CYSLTR2CYSLTR1MAPTBIDMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103119104-B Aqueous mixtures comprising aminoalkyl-containing polyorganosiloxanes and silicone resins WACKER CHEMIE AG 2015-03-25 CN disclosed